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  2. Sertraline - Wikipedia

    en.wikipedia.org/wiki/Sertraline

    Sertraline, sold under the brand name Zoloft among others, is an antidepressant medication of the selective serotonin reuptake inhibitor (SSRI) class [10] used to treat major depressive disorder, generalized anxiety disorder, social anxiety disorder, obsessive–compulsive disorder (OCD), panic disorder, and premenstrual dysphoric disorder. [11]

  3. Liverpool University Neuroleptic Side-Effect Rating Scale

    en.wikipedia.org/wiki/Liverpool_University...

    The LUNSERS is designed to monitor medication-induced side effects. This psychiatric assessment tools allows for the monitoring of side effects related to neuroleptic (or anti-psychotic) medications. The test is a self-reported check-tick box format with a predefined scale from "not at all" to "very much".

  4. Selective serotonin reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/Selective_serotonin...

    Paroxetine was the first drug to be approved for social anxiety disorder and it is considered effective for this disorder; sertraline and fluvoxamine were later approved for it as well. Escitalopram and citalopram are used off-label with acceptable efficacy, while fluoxetine is not considered to be effective for this disorder. [ 22 ]

  5. Serotonin reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/Serotonin_reuptake_inhibitor

    A serotonin reuptake inhibitor (SRI) is a type of drug which acts as a reuptake inhibitor of the neurotransmitter serotonin (5-hydroxytryptamine, or 5-HT) by blocking the action of the serotonin transporter (SERT). This in turn leads to increased extracellular concentrations of serotonin and, therefore, an increase in serotonergic ...

  6. Development and discovery of SSRI drugs - Wikipedia

    en.wikipedia.org/wiki/Development_and_discovery...

    Sertraline is the second most potent inhibitor of 5-HT re-uptake which has two very interesting characteristics that distinguish it i.e. sertraline's (1) inhibiting effect on DAT and NET and (2) the binding to sigma-1 (σ 1) receptor in CNS. [18]

  7. Antidepressant Sertraline taken by Thomas Kingston before ...

    www.aol.com/antidepressant-sertraline-taken...

    The antidepressants taken by Thomas Kingston before he killed himself have ben flagged more than 40 times by coroners, it has been found. The 45-year-old husband of Lady Gabriella Windsor took his ...

  8. ATC code N06 - Wikipedia

    en.wikipedia.org/wiki/ATC_code_N06

    ATC code N06 Psychoanaleptics is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.

  9. Desmethylsertraline - Wikipedia

    en.wikipedia.org/wiki/Desmethylsertraline

    Desmethylsertraline (DMS), also known as norsertraline, is an active metabolite of the antidepressant drug sertraline.Like sertraline, desmethylsertraline acts as a monoamine reuptake inhibitor, and may be responsible for some of its parent's therapeutic benefits; however, the effects of DMS's main activity of increasing serotonin levels via binding to the serotonin transporter appears to be ...