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Multiple system atrophy (MSA) is a rare neurodegenerative disorder [1] characterized by tremors, slow movement, muscle rigidity, postural instability (collectively known as parkinsonism), autonomic dysfunction and ataxia.
They include multiple system atrophy (MSA), progressive supranuclear palsy (PSP), and corticobasal degeneration (CBD). Dementia with Lewy bodies (DLB), may or may not be part of the PD spectrum, but it is increasingly recognized as the second-most common type of neurodegenerative dementia after Alzheimer's disease.
Gregor Karl Wenning (21 March 1964 – 11 February 2024) was a German neurologist best known for his clinical and scientific work in Parkinson's disease and atypical Parkinsonian disorders, particularly multiple system atrophy (MSA).
Such "primary" dysautonomias are distinguished from secondary dysautonomias, where the dysfunction of the autonomic nervous system is believed to be caused by another disease (e.g. diabetes). [2] Diseases categorized as primary autonomic failure usually include pure autonomic failure and multiple system atrophy.
Perry died at home of the rare disease, multiple system atrophy. At first she was diagnosed as having Parkinson's disease but that was later defined as Multiple System Atrophy, aka Parkinson plus syndrome. [6]
[12] [13] Further research identified multiple causes for these syndromic findings, now grouped as primary autonomic disorders (also called primary dysautonomia), including Pure Autonomic Failure, Multiple System Atrophy, and Parkinson's. The primary differentiating characteristic of Pure autonomic failure is decreased circulation and synthesis ...
Her laboratory focuses on identifying genetic causes of neurodegenerative diseases, such as dementia with Lewy bodies, multiple system atrophy, and frontotemporal dementia. [2] Her work in neurogenetics has contributed to a better understanding of diseases such as Alzheimer's disease and Parkinson's disease. [3]
Download as PDF; Printable version; In other projects Wikidata item; ... Multiple system atrophy; Mycothiol, an unusual thiol that is found in Actinobacteria; Computing