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Cerebral atrophy is a common feature of many of the diseases that affect the brain. [1] Atrophy of any tissue means a decrement in the size of the cell, which can be due to progressive loss of cytoplasmic proteins. In brain tissue, atrophy describes a loss of neurons and the connections between them.
The brain is very complex, and is composed of many different areas and types of tissue, or matter. The different functions of different tissues in the brain may be more or less susceptible to age-induced changes. [6] The brain matter can be broadly classified as either grey matter, or white matter.
Brain volume continues to decrease as we age—including the frontal lobe and hippocampus, the areas responsible for cognitive functions—with the rate of shrinkage increasing by around age 60.
The part of the brain most affected by Alzheimer's is the hippocampus. Other parts that show atrophy (shrinking) include the temporal and parietal lobes. Although this pattern of brain shrinkage suggests Alzheimer's, it is variable and a brain scan is insufficient for a diagnosis.
Tracking silent brain changes is key for such research. ... differences in brain shrinkage and cognitive test scores between the two groups became apparent, the study found.
A new study found that sleep quality issues in early middle-age are associated with accelerated brain aging and cognitive problems later in life. ... where the level of brain shrinkage corresponds ...