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Langerhans cell histiocytosis (LCH) is an abnormal clonal proliferation of Langerhans cells, abnormal cells deriving from bone marrow and capable of migrating from skin to lymph nodes. Symptoms range from isolated bone lesions to multisystem disease . [ 1 ]
Diffuse large B-cell lymphoma leg type: CD117: Mast cell: Mastocytosis: CD138: Plasma cell: Multiple myeloma Plasmablastic lymphoma: CD207 (Langerin) Langerhans cell: Langerhans cell histiocytosis: Chloracetate esterase (Leder) Mast cell: Mastocytosis: Chromogranin A: Merkel cell carcinoma: Cystokeratin 7: Paget's disease (breast and ...
Congenital self-healing reticulohistiocytosis is a condition that is a self-limited form of Langerhans cell histiocytosis ... nodes in 50% of Histiocytosis cases. [3 ...
X-type histiocytoses are a clinically well-defined group of cutaneous syndromes characterized by infiltrates of Langerhans cells, as opposed to Non-X histiocytosis in which the infiltrates contain monocytes/macrophages. [1]: 720 Conditions included in this group are: [1]: 720–4 Congenital self-healing reticulohistiocytosis
Letterer–Siwe disease, (LSD) or Abt-Letterer-Siwe disease, is one of the four recognized clinical syndromes of Langerhans cell histiocytosis (LCH) and is the most severe form, involving multiple organ systems such as the skin, bone marrow, spleen, liver, and lung. Oral cavity and gastrointestinal involvement may also be seen.
Langerhans cell histiocytosis (LCH) I: D76.0: Langerhans-cell histiocytosis Juvenile xanthogranuloma (JXG) II: D76.3: non-Langerhans-cell histiocytosis Hemophagocytic lymphohistiocytosis (HLH) II: D76.1: non-Langerhans-cell histiocytosis Niemann–Pick disease: II: E75.2: non-Langerhans-cell histiocytosis Sea-blue histiocytosis: II – non ...
First described in 1961 (where they were simply termed "characteristic granules"), [2] they are solely found in Langerhans cells. [1] Although part of normal Langerhans cell histology, they also provide a mechanism to differentiate Langerhans cell histiocytoses (which are a group of rare conditions collectively known as histiocytoses ) from ...
Non-Langerhans cell histiocytosis; Non-X histiocytosis; P. Progressive nodular histiocytosis; X. X-type histiocytosis This page was last edited on 27 November 2020 ...