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These treatments work by rehydrating the keloid scar tissue and regulating collagen production, prompting skin to soften and flatten. Follow the manufacturer’s instructions for best results.
The exact mechanism of action of silicone gel sheeting has not been fully studied. Currently, many proposed mechanisms explain the efficacy of such treatment, including the occlusion and hydration effect, increased body surface temperature, polarized electric charge, immunological effects, etc. [9] The occlusion and hydration effect is the most studied mechanism of action.
A long-term course of corticosteroid injections into the scar may help flatten and soften the appearance of keloid or hypertrophic scars. [54] Topical steroids are ineffective. [55] However, clobetasol propionate can be used as an alternative treatment for keloid scars. [56]
Keloids tend to have a genetic component, which means one is more likely to have keloids if one or both of their parents has them. However, no single gene has yet been identified which is a causing factor in keloid scarring but several susceptibility loci have been discovered, most notably in Chromosome 15.
A hypertrophic scar is a cutaneous condition characterized by deposits of excessive amounts of collagen which gives rise to a raised scar, but not to the degree observed with keloids. [1] Like keloids, they form most often at the sites of pimples, body piercings, cuts and burns. They often contain nerves and blood vessels.
Scarification involves scratching, etching, burning/branding, or superficially cutting designs, pictures, or words into the skin as a permanent body modification or body art. The body modification can take roughly 6–12 months to heal.
When given systemically, tranilast appears to cause liver damage; in a large well-conducted clinical trial it caused elevated transaminases three times the upper limit of normal in 11 percent of patients, as well as anemia, kidney failure, rash, and problems urinating.
Because the nose is the anchor-feature of the face, an aesthetically proportionate nose balances the physiognomic features of a person. Non-surgical correction is considered for patients with a treatment-suitable aesthetic defect, or a defect resulting from a surgical rhinoplasty (either primary or secondary).