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According to Dasgupta, the resulting brain cell damage can cause cognitive decline and increase the risk of vascular dementia — a form of dementia characterized by disruption to the brain’s ...
Some researchers are investigating how metformin, a common drug used to treat diabetes, may help prolong healthspan and lifespan. What evidence is there to support this notion?
Metformin helps manage blood sugar in people with type 2 diabetes in a few different ways: It helps the body respond better to the insulin it makes naturally, decreases the amount of sugar the ...
A 2017 review found that people with diabetes who were taking metformin had lower all-cause mortality. [231] They also had reduced cancer and cardiovascular disease compared with those on other therapies. [231] In people without diabetes, metformin does not appear to reduce the risk of cancer and cardiovascular disease. [237]
LATE is a term that describes a prevalent medical condition with impaired memory and thinking in advanced age, often culminating in the dementia clinical syndrome. [1] In other words, the symptoms of LATE are similar to those of Alzheimer's disease. The acronym LATE stands for Limbic-predominant Age-related TDP-43 Encephalopathy.
DLB is diagnosed when cognitive symptoms begin before or at the same time as parkinsonism. Parkinson's disease dementia is the diagnosis when Parkinson's disease is well established before the dementia occurs; that is, the onset of dementia is more than a year after the onset of parkinsonian symptoms. [9]