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Björk–Shiley valve, as depicted in patent #US003824629. The Björk–Shiley valve is a mechanical artificial heart valve. The valve was co-invented by American engineer Donald Shiley and Swedish heart surgeon Viking Björk. Beginning in 1971, it has been used to replace aortic valves and mitral valves. It was the first successful tilting ...
The Sorin Group was a medical products group based in Italy, with significant operations in France, the United States, and Japan, specializing in cardiac devices. [1] Its product lines include [2] replacement heart valves, oxygenators, perfusion tubing sets, cardiothoracic surgery accessories, data monitoring, heart-lung machines, autotransfusion systems, and cannulae, and a line of blood ...
Shiley began working at Edwards Laboratories, located in Orange County, California, south of Los Angeles, the first manufacturer of artificial heart-valves. [2] Later he established his own company, Shiley Laboratories, in the same area. His first valve was developed together with the American heart-surgeon Kay, and was the first disc heart-valve.
Shiley may refer to: Bjork–Shiley valve, mechanical heart valve prosthesis; Donald Shiley, one of the co-inventors of Pfizer's Bjork-Shiley heart valve;
14. Penumbra, Inc. (NYSE:PEN) Market Cap as of November 18: $7.34 B . Number of Hedge Fund Holders: 27. Penumbra, Inc. (NYSE:PEN) is a medical device company that manufactures products for the ...
In 1968, he collaborated with American engineer Donald Shiley to develop the Björk–Shiley valve, a mechanical prosthetic heart valve. It was the first "tilting disc valve", used to replace the aortic or mitral valve. Many modifications followed, including the convexo-concave valve. The convexo-concave valve had defects in form of strut ...
Pfizer purchased Shiley in 1979, at the onset of its Convexo-Concave valve ordeal, involving the Bjork–Shiley valve. Approximately 500 people died when defective heart valves fractured and, in 1994, Pfizer agreed to pay $10.75 million to settle claims by the United States Department of Justice that the company lied to get approval for the valves.
Pfizer laboratories, the drug manufacturer and owner of Shiley, stopped all manufacturing activities of Shiley Laboratory, with a view to liquidate the company. Consequently, not only was the Bjork-Shiley valve (the culprit) affected by this action, but all other products – valves, oxygenators, catheters, etc. - went out of production.