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  2. Sequence alignment - Wikipedia

    en.wikipedia.org/wiki/Sequence_alignment

    Read: CACGTAG—TA CIGAR: 2S5M2D2M where: 2S = 2 soft clipping (could be mismatches, or a read longer than the matched sequence) 5M = 5 matches or mismatches 2D = 2 deletions 2M = 2 matches or mismatches The original CIGAR format from the exonerate alignment program did not distinguish between mismatches or matches with the M character.

  3. Britten–Davidson model - Wikipedia

    en.wikipedia.org/wiki/Britten–Davidson_model

    The Britten–Davidson model, [1] [2] also known as the gene-battery model, [3] is a hypothesis for the regulation of protein synthesis in eukaryotes.Proposed by Roy John Britten and Eric H. Davidson in 1969, the model postulates four classes of DNA sequence: an integrator gene, a producer gene, a receptor site, and a sensor site.

  4. Transcription (biology) - Wikipedia

    en.wikipedia.org/wiki/Transcription_(biology)

    Transcription is the process of copying a segment of DNA into RNA for the purpose of gene expression. Some segments of DNA are transcribed into RNA molecules that can encode proteins, called messenger RNA (mRNA). Other segments of DNA are transcribed into RNA molecules called non-coding RNAs (ncRNAs).

  5. Gene expression - Wikipedia

    en.wikipedia.org/wiki/Gene_expression

    General transcription factors bind to the promoter. When a transcription factor is activated by a signal (here indicated as phosphorylation shown by a small red star on a transcription factor on the enhancer) the enhancer is activated and can now activate its target promoter. The active enhancer is transcribed on each strand of DNA in opposite ...

  6. Sequence logo - Wikipedia

    en.wikipedia.org/wiki/Sequence_logo

    A consensus logo is a simplified variation of a sequence logo that can be embedded in text format. Like a sequence logo, a consensus logo is created from a collection of aligned protein or DNA/RNA sequences and conveys information about the conservation of each position of a sequence motif or sequence alignment [1] [4].

  7. DNA and RNA codon tables - Wikipedia

    en.wikipedia.org/wiki/DNA_and_RNA_codon_tables

    This suggests that early ribosomes read the second codon position most carefully, to control hydrophobicity patterns in protein sequences. The first table—the standard table—can be used to translate nucleotide triplets into the corresponding amino acid or appropriate signal if it is a start or stop codon. The second table, appropriately ...

  8. MADS-box - Wikipedia

    en.wikipedia.org/wiki/MADS-box

    The MADS box is a conserved sequence motif.The genes which contain this motif are called the MADS-box gene family. [1] The MADS box encodes the DNA-binding MADS domain. The MADS domain binds to DNA sequences of high similarity to the motif CC[A/T] 6 GG termed the CArG-box. [2]

  9. Bacterial transcription - Wikipedia

    en.wikipedia.org/wiki/Bacterial_transcription

    Transcription is the process of copying DNA into RNA, usually mRNA.. Bacterial transcription is the process in which a segment of bacterial DNA is copied into a newly synthesized strand of messenger RNA (mRNA) with use of the enzyme RNA polymerase.