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  2. Decitabine - Wikipedia

    en.wikipedia.org/wiki/Decitabine

    Decitabine (i.e., 5-aza-2′-deoxycytidine), sold under the brand name Dacogen among others, acts as a nucleic acid synthesis inhibitor. [4] It is a medication for the treatment of myelodysplastic syndromes, a class of conditions where certain blood cells are dysfunctional, and for acute myeloid leukemia (AML). [5] Chemically, it is a cytidine ...

  3. Decitabine/cedazuridine - Wikipedia

    en.wikipedia.org/wiki/Decitabine/cedazuridine

    Decitabine/cedazuridine was approved for medical use in the United States and Canada in July 2020, [7] [8] [9] [12] and in the European Union in September 2023. [6]The U.S. Food and Drug Administration (FDA) granted the application of decitabine combined with cedazuridine priority review and orphan drug designation.

  4. Hypomethylating agent - Wikipedia

    en.wikipedia.org/wiki/Hypomethylating_agent

    A hypomethylating agent (or demethylating agent [1]) is a drug that inhibits DNA methylation: the modification of DNA nucleotides by addition of a methyl group.Because DNA methylation affects cellular function through successive generations of cells without changing the underlying DNA sequence, treatment with a hypomethylating agent is considered a type of epigenetic therapy.

  5. A New Study Says This Commonly-Prescribed Medication ... - AOL

    www.aol.com/study-says-commonly-prescribed...

    While weight loss and type 2 diabetes drugs can truly be life-changing for many people, Dr. Landsverk points out that these drugs are expensive and some people experience adverse side effects.

  6. 23 of the Best Sex Toys for Women That Will Seriously Rock ...

    www.aol.com/15-life-changing-sex-toys-212100813.html

    1. Better Love Butterfly. Best Overall Sex Toy. Made for solo or partner use, this vibrator is a top seller. The handle shape makes it super easy to maneuver and it has ten vibration modes with ...

  7. Nutritionists Explain Whether Women Over 50 Can Try ... - AOL

    www.aol.com/nutritionists-explain-whether-women...

    “IF can be safe for someone over the age of 50 if they are not a type 2 or type 1 diabetic who requires insulin, has hypoglycemia, or are on medications that require consumption with food ...

  8. Demethylating agent - Wikipedia

    en.wikipedia.org/wiki/Demethylating_agent

    Azacitidine and decitabine are marketed as Vidaza and Dacogen respectively. Azacitidine is the first drug to be approved by FDA for treating MDS and has been given orphan drug status. [ 2 ] [ 3 ] Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells. [ 4 ]

  9. What you should know about the latest obesity medication ...

    www.aol.com/news/obesity-medication-zepbound...

    Dr. Leana Wen: Both are injection medications that are intended to be used once a week. They were both first approved to treat type 2 diabetes, and clinical trials also showed that they induced a ...