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Hormonal breast enhancement or augmentation is a highly experimental potential medical treatment for the breasts in which hormones or hormonal agents such as estrogen, progesterone, growth hormone (GH), and insulin-like growth factor 1 (IGF-1) are utilized or manipulated to produce breast enlargement in women.
There have been some claims that zearalenone can increase the size of breasts in humans, but there are no tests of efficacy or safety. [2]: 1345 Zearalenone, produced by a toxic fungus, is a mycoestrogen that stimulates the growth of breast cancer cells, increases the chance of estrogen dependent breast cancer, and may reduce fertility. [9]
Estradiol is a naturally occurring and bioidentical estrogen, or an agonist of the estrogen receptor, the biological target of estrogens like endogenous estradiol. [10] Due to its estrogenic activity, estradiol has antigonadotropic effects and can inhibit fertility and suppress sex hormone production in both women and men.
Side effects of estradiol valerate include breast tenderness, breast enlargement, nausea, headache, and fluid retention. [15] [13] [14] Estradiol valerate is an estrogen and hence is an agonist of the estrogen receptor, the biological target of estrogens like estradiol. [5] [4] [16] It is an estrogen ester and a prodrug of estradiol in the body.
[7] [26] Receptors for prolactin and other hormones including insulin-like growth factor 1, insulin-like growth factor 2, luteinizing hormone, progesterone, and human chorionic gonadotropin have been found in male breast tissue, but the impact of these various hormones on gynecomastia development is not well understood.
Menopause and sex lives at the intersection of women’s pain, pleasure, and aging, all topics that somehow still—in 2023—make doctors (and society at large) glitch, leaving women to suffer in ...