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Synovitis causes joint tenderness or pain, swelling and hard lumps, called nodules. When associated with rheumatoid arthritis, swelling is a better indicator than tenderness. The joints in your hands and fingers feel painful when pressed and when moving or gripping anything.
In women, many cases seem to begin at puberty. Episodes of knee swelling may coincide the menstrual cycle. In nearly all case reports, pregnancy seems to suppress the condition but after birth, during lactation, it returns. [1] In the main, patients are mostly free of other symptoms. Fever is rare.
Transient synovitis is a diagnosis of exclusion. [4] The diagnosis can be made in the typical setting of pain or limp in a young child who is not generally unwell and has no recent trauma. There is a limited range of motion of the hip joint. Nevertheless, children with transient synovitis of the hip can usually weight bear.
Although sonography is extremely sensitive in detecting increased synovial fluid, it is nonspecific and cannot be used with accuracy to determine the type of fluid. Transient synovitis of the hip, despite being the most frequent cause of pain in children between 3 and 10 years, remains a diagnosis of exclusion.
[16]: 1098 Synovitis can lead to tethering of tissue with loss of movement and erosion of the joint surface causing deformity and loss of function. [2] The fibroblast-like synoviocytes (FLS), highly specialized mesenchymal cells found in the synovial membrane, have an active and prominent role in these pathogenic processes of the rheumatic joints.
Remitting seronegative symmetrical synovitis with pitting edema (or sometimes RS 3 PE) is a rare syndrome identified by symmetric polyarthritis, synovitis, acute pitting edema (swelling) of the back of the hands and/or feet, and a negative serum rheumatoid factor. [2]
IBS symptoms in women can also be triggered or worsened by menstruation, though the reason why isn't completely clear. Stress can also spark symptoms of IBS. "Some people say the GI tract is a ...
The incidence of diagnosis of the condition is higher in women than in men. [11] The syndrome commonly occurs during and, even more so, after pregnancy . [ 15 ] Contributory factors may include hormonal changes, fluid retention and—again, more debatably—increased housework and lifting.