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Disulfiram is a medication used to support the treatment of chronic alcoholism by producing an acute sensitivity to ethanol (drinking alcohol). Disulfiram works by inhibiting the enzyme aldehyde dehydrogenase (specifically the ALDH2 enzyme [3]), causing many of the effects of a hangover to be felt immediately following alcohol consumption.
A disulfiram-like drug is a drug that causes an adverse reaction to alcohol leading to nausea, vomiting, flushing, dizziness, throbbing headache, chest and abdominal discomfort, and general hangover-like symptoms among others.
Disulfiram-like drugs that produce sensitivity to the toxic effects of alcohol ... Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; ...
But this Nov. 7 proposal doesn't immediately take oral phenylephrine off the market. The public has six months to comment on the proposed order and to provide any additional data for the FDA to ...
Voluntarily withdrawn from US market because of risk of Progressive multifocal leukoencephalopathy (PML). Returned to market July 2006. Nefazodone: 2004 Europe, Australia, New Zealand and Canada [35] [36] [37] Branded version withdrawn by originator in several countries in 2007 for hepatotoxicity. Generic versions available. Still available in ...
Of course, compliance is still an issue in general but the drug remains in the body for a long time and many make note of that as reducing their alcohol intake out of abject fear. As acetaldehyde toxicity is beyond discomforting and may even cause death in severe cases, I can find a few examples on the internet of those taking the medication ...