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The prefrontal cortex has been defined based on cytoarchitectonics by the presence of a cortical granular layer IV.It is not entirely clear who first used this criterion. Many of the early cytoarchitectonic researchers restricted the use of the term prefrontal to a much smaller region of cortex including the gyrus rectus and the gyrus rostralis (Campbell, 1905; G. E. Smith, 1907; Brodmann ...
Many of our complex behaviors and mental activities require simultaneous engagement of multiple tasks, and they suggest the anterior prefrontal cortex may perform a domain-general function in these scheduling operations. Thus, the frontopolar cortex shares features with the central executive in Baddeley's model of working memory.
Brodmann mapped the human brain based on the varied cellular structure across the cortex and identified 52 distinct regions, which he numbered 1 to 52. These regions, or Brodmann areas, correspond with diverse functions including sensation, motor control, and cognition. [1]
Cortex Primary motor cortex (Precentral gyrus, M1) Premotor cortex; Supplementary motor cortex; Prefrontal cortex. Orbitofrontal cortex; Dorsolateral prefrontal cortex; Ventrolateral prefrontal cortex; Dorsomedial prefrontal cortex; Ventromedial prefrontal cortex; Gyri. Superior frontal gyrus; Middle frontal gyrus; Inferior frontal gyrus
The prefrontal cortex, being a central hub for executive functions, relies on the input from the mesocortical pathway to modulate and fine-tune cognitive processes essential for goal-directed behavior and decision-making. [20] Dysregulation of the neurons in this pathway has been connected to ADHD. [16]
Brodmann area 9, or BA9, refers to a cytoarchitecturally defined portion of the frontal cortex in the brain of humans and other primates. Its cytoarchitecture is referred to as granular due to the concentration of granule cells in layer IV. [1] It contributes to the dorsolateral and medial prefrontal cortex.
The dorsomedial prefrontal cortex (dmPFC [1] [2] or DMPFC [3] [4] is a section of the prefrontal cortex in some species' brain anatomy. It includes portions of Brodmann areas BA8 , BA9 , BA10 , BA24 and BA32 , [ 5 ] although some authors identify it specifically with BA8 and BA9 .
The mesocortical pathway is a dopaminergic pathway that connects the ventral tegmentum to the prefrontal cortex. It is one of the four major dopamine pathways in the brain . It is essential to the normal cognitive function of the dorsolateral prefrontal cortex (part of the frontal lobe), and is thought to be involved in cognitive control ...