Ads
related to: igg monoclonal gammopathy treatment- Find An Infusion Center
Learn About The Treatment Cycle &
Locate The Nearest Infusion Center.
- Sign Up For Updates
Get Resources, Treatment Support
& Tools To Talk To Your Doctor.
- Clinical Trial Results
Learn About The Effectiveness &
Safety Of RYSTIGGO®.
- Patient Resources
Download Brochures. Connect With
The Community & Support Groups.
- Find An Infusion Center
Search results
Results From The WOW.Com Content Network
Monoclonal gammopathy, also known as paraproteinemia, is the presence of excessive amounts of myeloma protein or monoclonal gamma globulin in the blood. It is usually due to an underlying immunoproliferative disorder or hematologic neoplasms , especially multiple myeloma .
Treatment is directed at the underlying monoclonal gammopathy, [11] and is intended to reduce the production of the monoclonal proteins [12] and may include bortezomib-based treatment, an autologous stem cell transplant, and if the patient is considered eligible, an organ transplant. [2]
Monoclonal gammopathy of undetermined significance (MGUS) is a plasma cell dyscrasia in which plasma cells or other types of antibody-producing cells secrete a myeloma protein, i.e. an abnormal antibody, into the blood; this abnormal protein is usually found during standard laboratory blood or urine tests.
In hematology, plasma cell dyscrasias (also termed plasma cell disorders and plasma cell proliferative diseases) are a spectrum of progressively more severe monoclonal gammopathies in which a clone or multiple clones of pre-malignant or malignant plasma cells (sometimes in association with lymphoplasmacytoid cells or B lymphocytes) over-produce and secrete into the blood stream a myeloma ...
Serum protein electrophoresis showing a paraprotein (spike/peak in the gamma zone) in a patient with multiple myeloma.. A myeloma protein is an abnormal antibody (immunoglobulin) or (more often) a fragment thereof, such as an immunoglobulin light chain, that is produced in excess by an abnormal monoclonal proliferation of plasma cells, typically in multiple myeloma or Monoclonal gammopathy of ...
The optimal treatment in MGRS is a clone directed therapy; where treatment is directed specifically to the cell line responsible for the pathologic monoclonal immunoglobulin or M-protein. [3] The goal of therapy is to preserve kidney function, reduce the risk of MGRS recurrence after kidney transplant and maintain a sustained hematologic response.
Ads
related to: igg monoclonal gammopathy treatment