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In non-segmental vitiligo (NSV), there is usually some form of symmetry in the location of the patches of depigmentation. New patches also appear over time and can be generalized over large portions of the body or localized to a particular area.
Vitiligo is a condition that causes the skin to begin to lose its pigmentation—or color—for no apparent reason, resulting in white patches that are especially noticeable in people whose skin ...
Nevus depigmentosus is a loss of pigment in the skin which can be easily differentiated from vitiligo. Although age factor has not much involvement in the nevus depigmentosus but in about 19% of the cases these are noted at birth. Their size may however grow in proportion to growth of the body.
The pigment loss can be partial (injury to the skin) or complete (caused by vitiligo). It can be temporary (from tinea versicolor) or permanent (from albinism). [1] Most commonly, depigmentation of the skin is linked to people born with vitiligo, which produces differing areas of light and dark skin. Monobenzone also causes skin depigmentation.
Hypopigmentation can be caused by hereditary conditions such as vitiligo, melasma, pityriasis versicolor, pityriasis alba, albinism, and fungal infections. [ 4 ] Hyperpigmentation results from an increase in melanin synthesis, which is mostly brought on by sun exposure, dermatological disorders, hormones, aging, genetic factors, skin injuries ...
Quadrichrome vitiligo; Reticular pigmented anomaly of the flexures (dark dot disease, Dowling–Degos' disease) Reticulate acropigmentation of Kitamura; Revesz syndrome; Riehl melanosis; Scratch dermatitis (flagellate pigmentation from bleomycin) Segmental vitiligo; Shah–Waardenburg syndrome
Vitiligo occurs in three different patterns. Segmental depigmentation means only one side of the body is affected, whereas generalized depigmentation means many parts of the body are affected. [34] Jackson's autopsy report states a "focal depigmentation of the skin" [35] (i.e., the depigmentation occurs on one or a few areas of the body). [34]
Poliosis is present in half of patients with segmental vitiligo. [ 5 ] Vogt-Koyanagi-Harada Syndrome (VKH): VKH is a systemic autoimmune disorder affecting melanin-containing tissues, leading to uveitis , meningitis , and poliosis, which often involves the eyebrows and eyelashes.