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Metastasis is a pathogenic agent's spreading from an initial or primary site to a different or secondary site within the host's body; [1] the term is typically used when referring to metastasis by a cancerous tumor. [2] The newly pathological sites, then, are metastases (mets).
Lymph node metastasis is the spread of cancer cells into a lymph node.. Lymph node metastasis is different from malignant lymphoma.Lymphoma is a cancer of lymph node, rather than cancer in the lymph node, because lymphoma originates from the lymph node itself, instead of originating elsewhere (e.g., the breast or colon) and spreading to the lymph nodes.
Also acid ionization constant or acidity constant. A quantitative measure of the strength of an acid in solution expressed as an equilibrium constant for a chemical dissociation reaction in the context of acid-base reactions. It is often given as its base-10 cologarithm, p K a. acid–base extraction A chemical reaction in which chemical species are separated from other acids and bases. acid ...
The dispersed tumors are called metastatic tumors, while the original is called the primary tumor. Almost all cancers can metastasize. [38] Most cancer deaths are due to cancer that has metastasized. [39] Metastasis is common in the late stages of cancer and it can occur via the blood or the lymphatic system or both. The typical steps in ...
Metastases can occur several years after the primary breast cancer, although it is sometimes diagnosed at the same time as the primary breast cancer or, rarely, before the primary breast cancer has been diagnosed. [2] Metastatic breast cancer cells frequently differ from the preceding primary breast cancer in properties such as receptor status.
CNS metastasis is the spread and proliferation of cancer cells from their original tumour to form secondary tumours in portions of the central nervous system. [ 1 ] The process of tumour cells invading distant tissue is complex and obscure, but modern technology has permitted an enhanced detection of metastasis .
HeLa cells, for example, are extremely prolific and have tetraploidy 12, trisomy 6, 8, and 17, and a modal chromosome number of 82 (rather than the normal diploid number of 46). [37] Small genetic mutations are most likely what begin tumorigenesis , but once cells begin the breakage-fusion-bridge (BFB) cycle , they are able to mutate at much ...
Metastasis is the most common cause of brain cancer, as primary tumors that originate in the brain are less common. [4] The most common sites of primary cancer which metastasize to the brain are lung, breast, colon, kidney, and skin cancer. Brain metastases can occur months or even years after the original or primary cancer is treated.