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Reported in 2001, a 13-year-old girl with short gut syndrome suddenly developed symptoms of intoxication after eating "excess carbohydrates and juices". She had no access to alcohol any time the symptoms were present. Her small intestine was colonized by two organisms: C. glabrata and S. cerevisiae. She was treated with fluconazole and her ...
Methanol has a moderate to high toxicity in humans. As little as 10 mL of pure methanol when drunk is metabolized into formic acid , which can cause permanent blindness by destruction of the optic nerve . 15 mL is potentially fatal, [ 1 ] although the median lethal dose is typically 100 mL (3.4 fl oz) (i.e. 1–2 mL/kg body weight of pure ...
Protein toxicity is the effect of the buildup of protein metabolic waste compounds, like urea, uric acid, ammonia, and creatinine. Protein toxicity has many causes, including urea cycle disorders, genetic mutations, excessive protein intake, and insufficient kidney function, such as chronic kidney disease and acute kidney injury .
Hippuric acid has long been used as an indicator of toluene exposure; [14] however, there appears to be some doubt about its validity. [15] There is significant endogenous hippuric acid production by humans; which shows inter- and intra-individual variation influenced by factors such as diet, medical treatment, alcohol consumption, etc. [15] This suggests that hippuric acid may be an ...
In addition to the toxicity of ethanol, the main psychoactive component of alcoholic beverages, other physiological symptoms may arise from the activity of acetaldehyde, a metabolite of alcohol. [11] These effects may not arise until hours after ingestion and may contribute to a condition colloquially known as a hangover.
Early symptoms include intoxication, vomiting and abdominal pain. [1] Later symptoms may include a decreased level of consciousness, headache, and seizures. [1] Long term outcomes may include kidney failure and brain damage. [1] Toxicity and death may occur after drinking even in a small amount [1] as ethylene glycol is more toxic than other diols.
Naphthalene is a major component of some mothballs.It repels moths as well as some animals. [citation needed]Since mothballs that contain naphthalene are considered hazards, safer alternatives have been developed, such as the use of 1,4-dichlorobenzene, however, 1,4-dichlorobenzene has been declared as a potential neurotoxin. 1,4-dichlorobenzene has been linked to potentially causing ...
Evidence indicates that amino acid balance has an important effect on protein nutrition and therefore on glutathione homeostasis. [28] Cysteine is an essential amino acid that acts as the limiting amino acid for glutathione synthesis in humans. Factors that increase demand for glutathione may increase demand for cysteine, and hence methionine.