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Disulfiram is a medication used to support the treatment of chronic alcoholism by producing an acute sensitivity to ethanol (drinking alcohol). Disulfiram works by inhibiting the enzyme aldehyde dehydrogenase (specifically the ALDH2 enzyme [3]), causing many of the effects of a hangover to be felt immediately following alcohol consumption.
How to stop drinking. Depending on whether you’re a light or heavy drinker, your strategy around cutting back will be different. “For a light drinker, you don’t really need to taper,” says ...
It might seem daunting to stop drinking alcohol for a whole month. But a 2020 Alcohol and Alcoholism study found that nearly 70% of people completed the Dry January Challenge in 2019.
A standard cup of coffee can contain anywhere from 95 to 200 mg of caffeine. That's a big range. The FDA cites 400 mg of caffeine per day "as an amount not generally associated with dangerous ...
No toxic effects have been observed with naltrexone in doses of up to 800 mg/day in clinical studies. [6] [3] The largest reported overdose of naltrexone, which was 1,500 mg in a female patient and was equivalent to an entire bottle of medication (30 × 50 mg tablets), was uneventful. [69] No deaths are known to have occurred with naltrexone ...
The brain regions most sensitive to harm from binge drinking are the amygdala and prefrontal cortex. [28] People in adolescence who experience repeated withdrawals from binge drinking show impairments of long-term nonverbal memory. Alcoholics who have had two or more alcohol withdrawals show more frontal lobe cognitive dysfunction than those ...
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