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The laminin B domain (also known as domain IV) is an extracellular module of unknown function. It is found in a number of different proteins that include, heparan sulphate proteoglycan from basement membrane, a laminin-like protein from Caenorhabditis elegans and laminin. Laminin IV domain is not found in short laminin chains (alpha4 or beta3).
Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene.
16776 Ensembl ENSG00000130702 ENSMUSG00000015647 UniProt O15230 Q61001 RefSeq (mRNA) NM_005560 NM_001081171 RefSeq (protein) NP_005551 NP_001074640 Location (UCSC) Chr 20: 62.31 – 62.37 Mb Chr 2: 179.82 – 179.87 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Laminin subunit alpha-5 is a protein that in humans is encoded by the LAMA5 gene. Function Components of the extracellular ...
16773 Ensembl ENSG00000196569 ENSMUSG00000019899 UniProt P24043 Q60675 RefSeq (mRNA) NM_000426 NM_001079823 NM_008481 RefSeq (protein) NP_000417 NP_001073291 NP_032507 Location (UCSC) Chr 6: 128.88 – 129.52 Mb Chr 10: 26.86 – 27.5 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Laminin subunit alpha-2 is a protein that in humans is encoded by the LAMA2 gene. Function Laminin, an ...
3912 16777 Ensembl ENSG00000091136 ENSMUSG00000002900 UniProt P07942 P02469 RefSeq (mRNA) NM_002291 NM_008482 RefSeq (protein) NP_002282 NP_032508 Location (UCSC) Chr 7: 107.92 – 108 Mb Chr 12: 31.32 – 31.38 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Laminin subunit beta-1 is a protein that in humans is encoded by the LAMB1 gene. Laminins, a family of extracellular matrix ...
The structure of lamins is composed of three units that are common among intermediate filaments: a central α-helical rod domain containing heptad repeats surrounded by globular N and C-terminal domains.
Laminin subunit alpha-3 is a protein that in humans is encoded by the LAMA3 gene. [5] [6] Function. Laminins are basement membrane components thought to mediate the ...
23928 Ensembl ENSG00000050555 ENSMUSG00000026840 UniProt Q9Y6N6 Q9R0B6 RefSeq (mRNA) NM_006059 NM_011836 RefSeq (protein) NP_006050 NP_035966 Location (UCSC) Chr 9: 131.01 – 131.09 Mb Chr 2: 31.78 – 31.84 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Laminin subunit gamma-3 also known as LAMC3 is a protein that in humans is encoded by the LAMC3 gene. Function Laminins, a family ...