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In medical diagnosis, test sensitivity is the ability of a test to correctly identify those with the disease (true positive rate), whereas test specificity is the ability of the test to correctly identify those without the disease (true negative rate). If 100 patients known to have a disease were tested, and 43 test positive, then the test has ...
Increasing the specificity of the test lowers the probability of type I errors, but may raise the probability of type II errors (false negatives that reject the alternative hypothesis when it is true). [a] Complementarily, the false negative rate (FNR) is the proportion of positives which yield negative test outcomes with the test, i.e., the ...
The positive predictive value (PPV), or precision, is defined as = + = where a "true positive" is the event that the test makes a positive prediction, and the subject has a positive result under the gold standard, and a "false positive" is the event that the test makes a positive prediction, and the subject has a negative result under the gold standard.
Content validity evidence involves the degree to which the content of the test matches a content domain associated with the construct. For example, a test of the ability to add two numbers should include a range of combinations of digits. A test with only one-digit numbers, or only even numbers, would not have good coverage of the content domain.
They use the sensitivity and specificity of the test to determine whether a test result usefully changes the probability that a condition (such as a disease state) exists. The first description of the use of likelihood ratios for decision rules was made at a symposium on information theory in 1954. [ 1 ]
In medical testing with binary classification, the diagnostic odds ratio (DOR) is a measure of the effectiveness of a diagnostic test. [1] It is defined as the ratio of the odds of the test being positive if the subject has a disease relative to the odds of the test being positive if the subject does not have the disease.
The value is chosen that gives the best combination of sensitivity and specificity. Both carbon-14 and carbon-13 urea breath tests have high sensitivity and specificity, though the carbon-13 test is preferred in certain populations due to its non-radioactive nature. [6] The test measures active H. pylori infection.
Specificity (statistics), the proportion of negatives in a binary classification test which are correctly identified; Sensitivity and specificity, in relation to medical diagnostics; Specificity (linguistics), whether a noun phrase has a particular referent as opposed to referring to any member of a class