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Simvastatin, sold under the brand name Zocor among others, is a statin, a type of lipid-lowering medication. [4] It is used along with exercise, diet, and weight loss to decrease elevated lipid levels . [ 4 ]
SAAM may affect people after long-term statin use even if they had no previous muscular side effects. [4] A differentiating feature between this and more benign statin side effects is SAAM typically has a late onset. While muscle pain (myalgia) is seen in 9-20% of patients treated with statins, it typically occurs in the first month of treatment.
A systematic review concluded that while clinical trial meta-analyses underestimate the rate of muscle pain associated with statin use, the rates of rhabdomyolysis are still "reassuringly low" and similar to those seen in clinical trials (about 1–2 per 10,000 person years). [75]
Statins are also sometimes prescribed to help lower cholesterol levels. Cheng-Han Chen, MD, a board-certified interventional cardiologist and medical director of the Structural Heart Program at ...
[17]: 12 Reintroduced as a dietary supplement in 2006; [17]: 13 in 2013 the FDA started work to ban it due to cardiovascular problems [18] Dinoprostone: 1990 UK Uterine hypotonus, fetal distress. [3] Dipyrone 1975 UK, US, Others Agranulocytosis, anaphylactic reactions. [3] Dithiazanine iodide: 1964 France, US
When examining the cost-effectiveness of statin use in older adults, the researchers report that statins were cost-effective, with the cost per quality-adjusted life years gained below £3,502 ...