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  2. Amyloidosis - Wikipedia

    en.wikipedia.org/wiki/Amyloidosis

    The deposition of amyloid proteins in the bone marrow without causing plasma cell dyscrasias is called amyloidoma. It is commonly found in cervical, lumbar, and sacral vertebrae. Those affected may be presented with bone pain due to bone lysis, lumbar paraparesis, and a variety of neurological symptoms. Vertebral fractures are also common.

  3. Cardiac amyloidosis - Wikipedia

    en.wikipedia.org/wiki/Cardiac_amyloidosis

    One such stain is Congo Red, which binds specifically to the amyloid deposit and can be characterized by various lighting methods. [7] Under polarized light, the amyloid deposits while show pathognomonic apple green birefringence, and under plain light the deposits will appear a light salmon pink color. [ 7 ]

  4. Light chain deposition disease - Wikipedia

    en.wikipedia.org/wiki/Light_chain_deposition_disease

    Light chain deposition disease can affect any organ. [3] Renal involvement is always present and can be identified by microscopic hematuria and proteinuria.Due to the gradual buildup of light chains from plasma filtration, renal function rapidly declines in the majority of patients with LCDD as either acute tubulointerstitial nephritis or rapidly progressing glomerulonephritis.

  5. Mysterious illness, dubbed "disease X," has killed dozens in ...

    www.aol.com/mysterious-illness-dubbed-disease-x...

    A mysterious illness, which the Africa Centers for Disease Control and Prevention is calling "disease X," has killed at least 31 people — mostly children — in the remote Panzi region of the ...

  6. Crystal-storing histiocytosis - Wikipedia

    en.wikipedia.org/wiki/Crystal-storing_histiocytosis

    The crystals do not birefringe and are negative when stained with Congo red stain, but may be positive by phosphotungstic acid hematoxylin and periodic acid-Schiff (PAS) staining. [3] [4] The most common immunoglobulin deposited in the crystals is IgG. [1] When the antibodies in the crystals are tested, they are almost always kappa light chain ...

  7. Plasma cell dyscrasias - Wikipedia

    en.wikipedia.org/wiki/Plasma_cell_dyscrasias

    In hematology, plasma cell dyscrasias (also termed plasma cell disorders and plasma cell proliferative diseases) are a spectrum of progressively more severe monoclonal gammopathies in which a clone or multiple clones of pre-malignant or malignant plasma cells (sometimes in association with lymphoplasmacytoid cells or B lymphocytes) over-produce and secrete into the blood stream a myeloma ...

  8. List of hematologic conditions - Wikipedia

    en.wikipedia.org/wiki/List_of_hematologic_conditions

    Myelophthisic anemia (also known as myelophthisis) is a severe kind of anemia found in some people with diseases that affect the bone marrow. Myelophthisis is the displacement of hemopoietic bone-marrow tissue into the peripheral blood, [51] either by fibrosis, tumors or granulomas. Neuroacanthocytosis: 29707: D054546

  9. Congo red - Wikipedia

    en.wikipedia.org/wiki/Congo_red

    Due to a color change from blue to red at pH 3.0–5.2, Congo red can be used as a pH indicator. Since this color change is an approximate inverse of that of litmus, it can be used with litmus paper in a simple parlor trick: add a drop or two of Congo red to both an acid solution and a base solution. Dipping red litmus paper in the red solution ...