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Score X: New areas of uptake unlikely to be related to lymphoma; Scores of 1 and 2 are considered to be negative and 4 and 5 are considered to be positive. "Score 3 should be interpreted according to the clinical context but in many Hodgkin Lymphoma patients indicates a good prognosis with standard treatment." [2]
The evidence is very uncertain about the effect of Nivolumab for patients with a Hodgkin's lymphoma e.g. on the overall survival. [50] Increased age is an adverse risk factor for Hodgkin lymphoma, but in general elderly people (≥ 60 years of age) without major comorbidities are sufficiently fit to tolerate therapy with curative intent.
1 point: Age 50–59, LDH 0.67-0.99 of the upper limit of normal, or WBC 6,700 to 9,999 cells/mcl; 2 points: Age 60–69, ECOG performance status of 2–4, LDH 1-1.49 times the upper limit of normal, or WBC 10,000-14,000 cells/mcl; 3 points: Age 70 or greater, LDH 1.5 times the upper limit of normal or greater, and WBC of 15,000 cells/mcl or ...
Women's Estrogen Lipid-Lowering Hormone Atherosclerosis Regression Trial (WELL-HART) Women's Health Initiative Estrogen Study (WHI-E) Women's Health Initiative Estrogen + Progestin Study (WHI-EP) Women's Health, Osteoporosis, Progestin, Estrogen (Women's HOPE) Women's International Study of Long-Duration Oestrogen After Menopause (WISDOM)
B symptoms are a clear negative prognostic factor in Hodgkin lymphoma. [2] The relevance of B symptoms in non-Hodgkin lymphoma is less clear, although B symptoms tend to correlate with disease that is either more widespread or of a higher histologic grade. [3]
Micrograph showing Hodgkin's lymphoma, a type of B cell lymphoma that is usually considered separate from other B cell lymphomas. Field stain. CT scan of primary B cell lymphoma in the left ilium, as diffuse cortical and trabecular thickening of the hemipelvis, mimicking Paget's disease. [2] There are numerous kinds of lymphomas involving B cells.
Ann Arbor staging is the staging system for lymphomas, both in Hodgkin's lymphoma (formerly designated Hodgkin's disease) and non-Hodgkin lymphoma (abbreviated NHL). It was initially developed for Hodgkin's, but has some use in NHL. It has roughly the same function as TNM staging in solid tumors.
Nodular sclerosing Hodgkin lymphoma ("NSHL") or Nodular sclerosis is a form of Hodgkin's lymphoma [1] that is the most common subtype of HL in developed countries. It affects females slightly more than males and has a median age of onset at ~28 years.
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