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Myelinogenesis is the formation and development of myelin sheaths in the nervous system, typically initiated in late prenatal neurodevelopment and continuing throughout postnatal development. [1] Myelinogenesis continues throughout the lifespan to support learning and memory via neural circuit plasticity as well as remyelination following ...
Myelin (/ ˈmaɪ.əlɪn / MY-ə-lin) is a lipid -rich material that surrounds nerve cell axons (the nervous system's electrical wires) to insulate them and increase the rate at which electrical impulses (called action potentials) pass along the axon. [1][2] The myelinated axon can be likened to an electrical wire (the axon) with insulating ...
Latin. incisura myelini. MeSH. D011901. TH. H2.00.06.2.03015. Anatomical terms of microanatomy. [edit on Wikidata] In neuroscience and anatomy, nodes of Ranvier (/ ˈrɑːnvieɪ / RAHN-vee-ay), [1][2] also known as myelin-sheath gaps, occur along a myelinated axon where the axolemma is exposed to the extracellular space.
Remyelination is the process of propagating oligodendrocyte precursor cells to form oligodendrocytes to create new myelin sheaths on demyelinated axons in the Central nervous system (CNS). This is a process naturally regulated in the body and tends to be very efficient in a healthy CNS. [1] The process creates a thinner myelin sheath than ...
Myelin basic protein (MBP) is a protein believed to be important in the process of myelination of nerves in the nervous system. The myelin sheath is a multi-layered membrane, unique to the nervous system, that functions as an insulator to greatly increase the velocity of axonal impulse conduction. [5] MBP maintains the correct structure of ...
Multiple sclerosis (MS) is an autoimmune disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged. [3] Being a demyelinating disease, MS disrupts the ability of parts of the nervous system to transmit signals, resulting in a range of signs and symptoms, including physical, mental, and sometimes psychiatric ...
In neuroscience, threshold potentials are necessary to regulate and propagate signaling in both the central nervous system (CNS) and the peripheral nervous system (PNS). Most often, the threshold potential is a membrane potential value between –50 and –55 mV, [1] but can vary based upon several factors. A neuron 's resting membrane ...
Multiple sclerosis is an inflammatory demyelinating disease of the CNS in which activated immune cells invade the central nervous system and cause inflammation, neurodegeneration, and tissue damage. The underlying cause is currently unknown. Current research in neuropathology, neuroimmunology, neurobiology, and neuroimaging, together with ...