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  2. ATM serine/threonine kinase - Wikipedia

    en.wikipedia.org/wiki/ATM_serine/threonine_kinase

    The ATM gene promoter was observed to be hypermethylated in 53% of small (impalpable) breast cancers [31] and was hypermethylated in 78% of stage II or greater breast cancers with a highly significant correlation (P = 0.0006) between reduced ATM mRNA abundance and aberrant methylation of the ATM gene promoter. [32]

  3. Guidelines say more women may need breast cancer gene test - AOL

    www.aol.com/news/2019-08-26-guidelines-say-more...

    Most cancer isn't caused by BRCA mutations — they account for 5 percent to 10 percent of breast cancers and 15 percent of ovarian cancers — so the gene tests aren't for everyone. But mutations ...

  4. Ataxia–telangiectasia - Wikipedia

    en.wikipedia.org/wiki/Ataxia–telangiectasia

    Women who are A–T carriers (who have one mutated copy of the ATM gene) have approximately a two-fold increased risk for the development of breast cancer compared to the general population. [19] [20] This includes all mothers of A–T children and some female relatives. The current consensus is that special screening tests are not helpful, but ...

  5. CHEK2 - Wikipedia

    en.wikipedia.org/wiki/CHEK2

    The estimated fraction of breast cancer attributed to this variant is reported to be around 1.2% in the US. [ 8 ] Two more CHEK2 gene mutations, CHEK2*S428F, an amino-acid substitution to the kinase domain in exon 11 and CHEK2*P85L, an amino-acid substitution in the N-terminal region (exon 1) have been found in the Ashkenazi Jewish population ...

  6. Blood test ‘could detect breast cancer up to two ... - AOL

    www.aol.com/blood-test-could-detect-breast...

    The Trial Early Serum Test Breast cancer (TESTBREAST) study includes 1,174 women in the Netherlands who are at a high risk of breast cancer, due to their family history or because they carry gene ...

  7. This blood test screens for 50 different types of cancer. Is ...

    www.aol.com/lifestyle/blood-test-screens-50...

    As with most blood tests, false-negatives can happen, meaning results could come back negative when a cancer does exist — although Grail reports that negative cancer test results from Galleri ...

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