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  2. Alzheimer's disease - Wikipedia

    en.wikipedia.org/wiki/Alzheimer's_disease

    FDA-approved radiopharmaceutical diagnostic agents used in PET for Alzheimer's disease are florbetapir (2012), flutemetamol (2013), florbetaben (2014), and flortaucipir (2020). [131] Because many insurance companies in the United States do not cover this procedure, its use in clinical practice is largely limited to clinical trials as of 2018. [132]

  3. Limbic-predominant age-related TDP-43 encephalopathy

    en.wikipedia.org/wiki/Limbic-predominant_age...

    [15] [16] [17] [10] A common combination of brain pathologies—with Alzheimer's disease pathology, Lewy body pathology, and LATE-NC in the same brain—tends to affect younger individuals (often <75 yrs of age) and, on average, is associated with more aggressive (faster) cognitive deterioration.

  4. Frontotemporal dementia - Wikipedia

    en.wikipedia.org/wiki/Frontotemporal_dementia

    Fluorine-18-fluorodeoxyglucose positron emission tomography scans classically show frontal and/or anterior temporal hypometabolism, which helps differentiate the disease from Alzheimer's disease, as the PET scan in Alzheimer's disease classically shows biparietal hypometabolism.

  5. US removes coverage curb on PET scans for Alzheimer's ... - AOL

    www.aol.com/news/u-agency-removes-coverage-curb...

    “Amyloid PET scans are a proven tool and can be an important part of Alzheimer’s diagnosis and treatment,” Maria Carrillo, chief science officer of the Alzheimer’s Association, said in a ...

  6. Pittsburgh compound B - Wikipedia

    en.wikipedia.org/wiki/Pittsburgh_compound_B

    11 C-PiB is currently the most studied and used radioligand for PET imaging of cerebral Aβ pathology. [2] This technique has been implicated in Alzheimer's disease research whereby scientists involved in this field are able to perform noninvasive in vivo neuroimaging studies using PET scans in brains of individuals with various degrees of dementia.

  7. Brain positron emission tomography - Wikipedia

    en.wikipedia.org/wiki/Brain_positron_emission...

    PET scanning is also used for diagnosis of brain disease, most notably because brain tumors, strokes, and neurondegenerative diseases (such as Alzheimer's disease and Parkinson's disease) all cause great changes in brain metabolism, which in turn causes detectable changes in PET scans. PET is probably most useful in early cases of certain ...

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