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Erectile dysfunction can be a consequence of vitamin D deficiency. Mechanisms may include the regulation of vascular stiffness, the production of vasodilating nitric oxide, and the regulation of vessel permeability. However, the clinical trial literature does not yet contain sufficient evidence that supplementation treats the problem.
PF-00446687 is a drug developed by Pfizer for the treatment of erectile dysfunction, which is a non-peptide agonist selective for the melanocortin receptor subtype MC 4.It was found to be active in preliminary human trials, with the 200mg dose being of similar effectiveness to 100mg sildenafil, though lower doses were ineffective.
Erectile dysfunction ... Vitamin D supplementation lowers atorvastatin and active ... Over the dose range of 10 to 80 mg/day total cholesterol was reduced by 27.0% to ...
Because of its antiandrogenic activity, spironolactone can cause breast tenderness, gynecomastia (breast development), feminization in general, and demasculinization, as well as sexual dysfunction including loss of libido and erectile dysfunction, although these side effects are usually confined to high doses of spironolactone. [109]
Mirodenafil belongs to the drug class PDE5 inhibitors, which includes avanafil, sildenafil, tadalafil, udenafil, and vardenafil, and is the first-line treatment for erectile dysfunction. Developed by SK Chemicals Life Science , mirodenafil is marketed in Korea under the trade name Mvix , offered both as tablets (50 mg and 100 mg) and as orally ...
Vitamin D 3 and vitamin K 2. [25] [26] [27] Clinical uses. ... To treat erectile dysfunction or in penile rehabilitation following surgery (PGE1 as alprostadil).
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