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Mucociliary clearance has a major role in pulmonary hygiene. MCC effectiveness relies on the correct properties of the airway surface liquid produced, both of the periciliary sol layer and the overlying mucus gel layer, and of the number and quality of the cilia present in the lining of the airways. [3] An important factor is the rate of mucin ...
Ambroxol is indicated as "secretolytic therapy in bronchopulmonary diseases associated with abnormal mucus secretion and impaired mucus transport. It promotes mucus clearance, facilitates expectoration and eases productive cough, allowing patients to breathe freely and deeply". [2] Ambroxol hydrochloride tablets in Japan
The trust was formed on 1 July 2006, following the merger of the Hereford & Worcester Ambulance Service NHS Trust, Coventry & Warwickshire Ambulance NHS Trust, and WMAS and Shropshire services. [3] On 1 October 2007, the service merged with Staffordshire Ambulance Service NHS Trust. [3] [4] It became an NHS foundation trust on 1 January 2013. [5]
Between 1948 and 1972 the NHS largely remained free of strikes, but nevertheless did experience some other industrial disputes. The foundation of the service was opposed by many doctors, particularly general practitioners, who feared that a state medical service would reduce their independence.
Mucokinetics: increase mucociliary transport (clearance) and transportability of mucus by cough [2] Mucoregulators : suppress underlying mechanisms of mucus hypersecretion [ 2 ] Alternatively, attacking the affinity between secretions and the biological surfaces is another avenue, which is used by abhesives and surfactants .
Airway clearance therapy is treatment that uses a number of airway clearance techniques to clear the respiratory airways of mucus and other secretions. [1] Several respiratory diseases cause the normal mucociliary clearance mechanism to become impaired resulting in a build-up of mucus which obstructs breathing, and also affects the cough reflex .