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The COX-2 enzyme was discovered in 1988 by Daniel Simmons, a Brigham Young University researcher. [30] The mouse COX-2 gene was cloned by UCLA scientist Harvey Herschman, a finding published in 1991. [31] The basic research leading to the discovery of COX-2 inhibitors has been the subject of at least two lawsuits.
The cost of one Euro in Indonesian rupiah's (from 2005). The rupiah declined from its relatively strengthened position at the end of the financial crisis, with the rupiah seeing the start of 2000 at Rp7,050 to the US dollar, but declining to Rp9,725 by the end of 2000, and reaching a low of Rp12,069 on 27 April 2001.
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All of the coxibs achieve sufficient brain concentrations to have a central analgesic effect, and all reduce prostaglandin formation in inflamed joints. All are well absorbed, but peak concentration may differ between the coxibs. The coxibs are highly protein-bound, and the published estimate of half-lives is variable between the coxibs. [17]
The Indonesian Wikipedia (Indonesian: Wikipedia bahasa Indonesia, WBI for short) is the Indonesian language edition of Wikipedia. It is the fifth-fastest-growing Asian-language Wikipedia after the Japanese, Chinese, Korean, and Turkish language Wikipedias. It ranks 25th in terms of depth among Wikipedias.
This list is sorted by the number of tickets sold nationwide, according to the filmindonesia.or.id. [1] However, the information on filmindonesia.or.id was accrued only from 2007, making some films that was released before 2007 are not included or do not have an accurate number of admissions.
The production of this film spent a budget of up to IDR 70 billion which was considered the largest for an Indonesian action film when it was released. [4] The film was released on 21 February 2019. The film stars Oka Antara, Verdi Solaiman, Chicco Jerikho , Arifin Putra, and Rio Dewanto.
Title Director Cast Genre Notes 1970: Ananda: Usmar Ismail: Bernapas dalam lumpur: 1971: Beranak Dalam Kubur: Horror: Tuan tanah Kedawung: Awaludin: 1972: Beranak dalam kubur