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Docetaxel induced pneumotoxicity is also a well recognized adverse effect which has to be identified timely and treated after withholding the drug. [8] Side effects are more common in people with liver problems. [6] Use during pregnancy may harm the baby. [6] Docetaxel is in the taxane family of medications. [9]
These side-effects can frequently be reduced or eliminated with antiemetic drugs. Low-certainty evidence also suggests that probiotics may have a preventative and treatment effect of diarrhoea related to chemotherapy alone and with radiotherapy. [ 86 ]
Although docetaxel, a drug used as regimen was found to be effective in treatment of CRPC in 2004, [17] using docetaxel caused serious side effects such as neuropathy and fatigue. [18] This is undesirable especially when most patients with prostate cancer are old-aged.
A number of these side effects are associated with the excipient used, Cremophor EL, a polyoxyethylated castor oil. Allergies to cyclosporine , teniposide , and other drugs delivered in polyoxyethylated castor oil may increase the risk of adverse reactions to paclitaxel.
The most common side effects of Journavx, according to the company’s website, include itching, muscle spasms, rash, and increased levels of an enzyme called creatine phosphokinase in the blood ...
Docetaxel, is a semi-synthetic analogue of paclitaxel, with a trade name Taxotere. Docetaxel has the minimal structure modifications at C13 side chain and C10 substitution showed more water solubility and more potency than paclitaxel.
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