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An antiemetic is a drug that is effective against vomiting and nausea. Antiemetics are typically used to treat motion sickness and the side effects of opioid analgesics, general anaesthetics, and chemotherapy directed against cancer. They may be used for severe cases of gastroenteritis, especially if the patient is dehydrated. [1] [2]
Rolapitant is used in combination with other antiemetic (anti-vomiting) agents in adults for the prevention of delayed nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy, including, but not limited to, highly emetogenic chemotherapy. [1]
The antiemetic action of metoclopramide is due to its antagonist activity at D 2 receptors in the chemoreceptor trigger zone in the brain — this action prevents nausea and vomiting triggered by most stimuli. [34] At higher doses, 5-HT 3 antagonist activity may also contribute to the antiemetic effect. [35] [failed verification]
Antiemetics act by inhibiting the receptor sites associated with emesis. Hence, anticholinergics, antihistamines, dopamine antagonists, serotonin antagonists, and cannabinoids are used as antiemetics. [36] Evidence to support the use of antiemetics for nausea and vomiting among adults in the emergency department is poor. [37]
Norovirus is a highly contagious virus that causes vomiting and diarrhea—and sometimes at the same time, ... Dr. Adalja says you can call your doctor about an antiemetic (anti-nausea) medication ...
It has a central antiemetic action and effectively prevents postoperative nausea and vomiting in adults using doses as low as 0.625 mg. . For treatment of nausea and vomiting, droperidol and ondansetron are equally effective; droperidol is more effective than metoclopramide. [8]