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  2. Cytotoxic T cell - Wikipedia

    en.wikipedia.org/wiki/Cytotoxic_T_cell

    Antigen presentation stimulates T cells to become either "cytotoxic" CD8+ cells or "helper" CD4+ cells.. A cytotoxic T cell (also known as T C, cytotoxic T lymphocyte, CTL, T-killer cell, cytolytic T cell, CD8 + T-cell or killer T cell) is a T lymphocyte (a type of white blood cell) that kills cancer cells, cells that are infected by intracellular pathogens such as viruses or bacteria, or ...

  3. CD8 - Wikipedia

    en.wikipedia.org/wiki/CD8

    The CD8 co-receptor is predominantly expressed on the surface of cytotoxic T cells, but can also be found on natural killer cells, cortical thymocytes, and dendritic cells. The CD8 molecule is a marker for cytotoxic T cell population. It is expressed in T cell lymphoblastic lymphoma and hypo-pigmented mycosis fungoides. [4]

  4. Suppressor-inducer T cell - Wikipedia

    en.wikipedia.org/wiki/Suppressor-inducer_T_cell

    Suppressor-inducer T cells are a specific subset of CD4 + T helper cells that "induce" CD8 + cytotoxic T cells to become "suppressor" cells. [1] Suppressor T cells are also known as CD25 + – Foxp3 + regulatory T cells (nTregs), and reduce inflammation .

  5. Regulatory T cell - Wikipedia

    en.wikipedia.org/wiki/Regulatory_T_cell

    All T cells derive from progenitor cells in the bone marrow, which become committed to their lineage in the thymus.All T cells begin as CD4-CD8-TCR- cells at the DN (double-negative) stage, where an individual cell will rearrange its T cell receptor genes to form a unique, functional molecule, which they, in turn, test against cells in the thymic cortex for a minimal level of interaction with ...

  6. T cell - Wikipedia

    en.wikipedia.org/wiki/T_cell

    Optimal CD8 + T cell response relies on CD4 + signalling. [44] CD4 + cells are useful in the initial antigenic activation of naive CD8 T cells, and sustaining memory CD8 + T cells in the aftermath of an acute infection. Therefore, activation of CD4 + T cells can be beneficial to the action of CD8 + T cells. [45] [46] [47]

  7. Primary cutaneous acral CD8 positive T cell ...

    en.wikipedia.org/wiki/Primary_cutaneous_acral...

    The diagnosis of CD8+ TLPD is strongly dependent on finding that: a) it presents as a very slowly growing and usually single nodule or plaque that consists of CD8+ T cells in the cutaneous tissues primarily but not exclusively of acral sites, particularly the ear, in adults; [14] b) the cells in these lesions are predominantly CD8+ T-cells that ...

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