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Thus, surgery is the most common treatment of this neoplasm. A case of giant ameloblastoma was recently reported and managed with total mandibulectomy and pectoralis major myocutaneous flap reconstruction. [15] A systematic review found that 79% of desmoplastic ameloblastoma cases were treated by resection.
The Ameloblastic Fibroma epithelial tissue could be confused with the most common odontogenic tumour, the Ameloblastoma. Therefore the mesenchymal component is histologically important in differential diagnosis. [7] The mesenchymal stroma in normal development is a rich myxoid connective tissue.
Initially, AFO was called as ameloblastic odontoma. Hooker in 1967 first used the term ameloblastic fibro-odontoma. [12] WHO classified odontogenic tumors for the first time in 1971 (1stedition).
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Typically, clinical signs and symptoms present with bony expansion, or infection. However, bony expansion is uncommon as odontogenic keratocysts grow due to increased epithelial turnover rather than osmotic pressure. When symptoms are present they usually take the form of pain, swelling and discharge due to secondary infection.
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Common symptoms of ameloblastic carcinomas are pain and swelling either localized in the jaw or throughout the entire face, dysphagia, and trismus.Less common symptoms include ulceration, loosening of the teeth, chronic epistaxis, facial pressure, and nasal dyspnea.