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If the lymph node or similar tissue is reactive, or otherwise benign, it should possess a mixture of kappa positive and lambda positive cells. If, however, one type of light chain is significantly more common than the other, the cells are likely all derived from a small clonal population, which may indicate a malignant condition, such as B-cell ...
The Lambda2 method, or Lambda2 vortex criterion, is a vortex core line detection algorithm that can adequately identify vortices from a three-dimensional fluid velocity field. [1] The Lambda2 method is Galilean invariant , which means it produces the same results when a uniform velocity field is added to the existing velocity field or when the ...
In some cells, antigens bind to recycled MHC class II molecules while they are in the early endosomes, while other cells such as dendritic cells internalize antigens via receptor-mediated endocytosis and create MHC class II molecules plus peptide in the endosomal-lysosomal antigen processing compartment which is independent of the synthesis of ...
CD163 (Cluster of Differentiation 163) is a protein that in humans is encoded by the CD163 gene. [5] CD163 is the high affinity scavenger receptor for the hemoglobin-haptoglobin complex [6] and in the absence of haptoglobin - with lower affinity - for hemoglobin alone. [7]
Lambda strains, mutated at specific sites, are unable to lysogenize cells; instead, they grow and enter the lytic cycle after superinfecting an already lysogenized cell. [ 3 ] The phage particle consists of a head (also known as a capsid ), [ 4 ] a tail, and tail fibers (see image of virus below).
50913 Ensembl ENSG00000205927 ENSMUSG00000039830 UniProt Q13516 Q9EQW6 RefSeq (mRNA) NM_005806 NM_016967 RefSeq (protein) NP_005797 NP_058663 Location (UCSC) Chr 21: 33.03 – 33.03 Mb Chr 16: 91.02 – 91.03 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Oligodendrocyte transcription factor (OLIG2) is a basic helix-loop-helix (bHLH) transcription factor encoded by the OLIG2 gene ...
Type 2 inflammation is a pattern of immune response. Its physiological function is to defend the body against helminths , but a dysregulation of the type 2 inflammatory response has been implicated in the pathophysiology of several diseases.
Furthermore, CD27 is expressed on both naïve and activated effector T cells as well as NK cells and activated B cells. [5] It is a type I transmembrane protein with cysteine-rich domains, but once T cells have become activated, a soluble form of CD27 can be shed. [5] [6]