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Copy number variation (CNV) is a phenomenon in which sections of the genome are repeated and the number of repeats in the genome varies between individuals. [1] Copy number variation is a type of structural variation: specifically, it is a type of duplication or deletion event that affects a considerable number of base pairs. [2]
Major DBMSs, including SQLite, [5] MySQL, [6] Oracle, [7] IBM Db2, [8] Microsoft SQL Server [9] and PostgreSQL [10] support prepared statements. Prepared statements are normally executed through a non-SQL binary protocol for efficiency and protection from SQL injection, but with some DBMSs such as MySQL prepared statements are also available using a SQL syntax for debugging purposes.
Copy number analysis is the process of analyzing data produced by a test for DNA copy number variation in an organism's sample. One application of such analysis is the detection of chromosomal copy number variation that may cause or may increase risks of various critical disorders.
Transact-SQL is central to using Microsoft SQL Server. All applications that communicate with an instance of SQL Server do so by sending Transact-SQL statements to the server, regardless of the user interface of the application. Stored procedures in SQL Server are executable server-side routines. The advantage of stored procedures is the ...
SQL Server 2008 and 2012 SSRS can also prepare reports in Microsoft Word (DOC) format, while third-party report generators offer additional output formats. Users can interact with the Report Server web service directly, or instead use Report Manager, a Web-based application that interfaces with the Report Server web service.
Multiplex ligation-dependent probe amplification (MLPA) is a variation of the multiplex polymerase chain reaction that permits amplification of multiple targets with only a single primer pair. [1] It detects copy number changes at the molecular level, and software programs are used for analysis.
In situations where the number of unique values of a column is far less than the number of rows in the table, column-oriented storage allow significant savings in space through data compression. Columnar storage also allows fast execution of range queries (e.g., show all records where a particular column is between X and Y, or less than X.)
Many biotechnology applications utilize mutated plasmids that replicate to high copy number. For example, pBR322 is a medium copy number plasmid (~20 copies/cell) from which several high copy number cloning vectors (>100 copies/cell) have been derived by mutagenesis, such as the well known pUC series. [1] This delivers the convenience of high ...