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Cohorts for Heart and Aging Research in Genomic Epidemiology, abbreviated CHARGE, is a consortium formed to facilitate meta-analyses of genome-wide association studies of aging and cardiovascular traits, and the replication of genotype–phenotype associations identified in such studies.
Aging is characterized by a progressive loss of physiological integrity, leading to impaired function and increased vulnerability to death. The hallmarks of aging are the types of biochemical changes that occur in all organisms that experience biological aging and lead to a progressive loss of physiological integrity, impaired function and, eventually, death.
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The main mechanisms identified as potential biomarkers of aging are DNA methylation, loss of histones, and histone modification. The uses for biomarkers of aging are ubiquitous and identifying a physical parameter of biological aging would allow humans to determine our true age, mortality, and morbidity. [10]
This is an accepted version of this page This is the latest accepted revision, reviewed on 2 February 2025. Biological process of getting older This article is about ageing specifically in humans. For the ageing of whole organisms including animals, see Senescence. For other uses, see Ageing (disambiguation). Part of a series on Human growth and development Stages Gamete Zygote Embryo Fetus ...
The journal publishes all types of original research articles, including studies conducted with human subjects and experimental models, as well as applied clinical, epidemiological, and healthcare policy papers related to cardiovascular and cerebrovascular diseases.
The European Journal of Preventive Cardiology is a peer-reviewed medical journal that covers research on the cardiovascular system. The journal's editor-in-chief is Prof Victor Aboyans (University of Limoges, France). It was established in 1994 as the European Journal of Cardiovascular Prevention & Rehabilitation and
The Australasian Journal on Ageing is a quarterly peer-reviewed scientific journal covering the fields of gerontology and geriatrics.It is published by Wiley on behalf of AJA Inc, which represents the Australian and New Zealand Society for Geriatric Medicine, COTA Australia and the Australian Association of Gerontology and the editor-in-chief is Mark Hughes (Southern Cross University).