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For non-prescription use, products with less than 0.3% delta-9 THC containing CBD, delta-8 THC, and other naturally-occurring cannabinoids derived from hemp (cannabis containing less than 0.3% delta-9 THC) are legal and unregulated [10] at the federal level, but legality and enforcement varies by state. [11] [12] [13]
Mark Stepnoski, former All-Pro offensive lineman for the Dallas Cowboys and Houston Oilers, served as president of the Texas chapter of the National Organization for the Reform of Marijuana Laws (Texas NORML) during the early 2000s. [100] [101] Texas Cannabis Collective, a pro-legalization group, was founded in 2016. [102]
Notes: · Reflects laws of states and territories, including laws which have not yet gone into effect. Does not reflect federal, tribal, or local laws. · Map does not show state legality of hemp-derived cannabinoids such as CBD or delta-8-THC, which have been legal at federal level since enactment of the 2018 Farm Bill
Following legal changes in the United States since around 2018, especially the legalisation of cannabis in an increasing number of states and the passage of the 2018 Farm Bill [12] which eased restrictions on the cultivation of industrial hemp, THC-O-acetate has become increasingly available as a recreational drug in the United States. [13]
Although the chemical formula for THC (C 21 H 30 O 2) describes multiple isomers, [10] the term THC usually refers to the delta-9-THC isomer with chemical name (−)-trans-Δ 9-tetrahydrocannabinol. It is a colorless oil.
Dronabinol is the principal psychoactive constituent enantiomer form, (−)-trans-Δ 9-tetrahydrocannabinol, found in Cannabis sativa L. plants, [8] but can also be synthesized in laboratory. Dronabinol does not include any other tetrahydrocannabinol (THC) isomers or any cannabidiol .
Δ-11-Tetrahydrocannabinol (Delta-11-THC, Δ 11-THC, Δ 9(11)-THC, exo-Tetrahydrocannabinol) is a rare isomer of tetrahydrocannabinol, developed in the 1970s. It can be synthesised from Δ 8 -THC by several different routes, [ 1 ] [ 2 ] [ 3 ] though only the (6aR, 10aR) enantiomer is known.
It retains psychoactive effects in animal studies with higher potency than Δ 8-THC but lower potency than 11-OH-Δ 9-THC. With widespread legal use of semi-synthetic Δ 8-THC in certain jurisdictions where Δ 9-THC remains illegal, 11-OH-Δ 8-THC is now an important metabolite for distinguishing between use of hemp-derived Δ 8-THC and natural ...