Ads
related to: indomethacin side effects in elderly
Search results
Results From The WOW.Com Content Network
The frequency and severity of side effects and the availability of better tolerated alternatives make indometacin today a drug of second choice. Its use in acute gout attacks and in dysmenorrhea is well-established because in these indications the duration of treatment is limited to a few days only, therefore serious side effects are not likely ...
NSAIDs with less side effects are more preferred in migraine therapy. [11] Prevention of pancreatitis. Rectal NSAIDs such as diclofenac and indomethacin are administered for the prevention of pancreatitis due to endoscopic retrograde cholangiopancreatography (ERCP). [12] ERCP is a technique for treating liver and pancreatic disease. [7]
Indometacin farnesil is a prodrug of the nonsteroidal anti-inflammatory drug (NSAID) indometacin, [1] designed to reduce the occurrence of side-effects by esterification of the carboxyl group on indometacin with farnesol.
Hemicrania continua generally responds only to indomethacin 25–300 mg daily, which must be continued long term. Unfortunately, gastrointestinal side effects are a common problem with indomethacin, which may require additional acid-suppression therapy to control. [10]
Amiodarone, some benzodiazepines, cyclosporine, diphenoxylate, indomethacin, itraconazole, propafenone, quinidine, quinine, spironolactone, and verapamil may lead to toxic levels and increased incidence of side effects. [8] Digoxin plasma concentrations may increase while on antimalarial medication hydroxychloroquine. [3]
Prostaglandin analogues such as misoprostol are used in treatment of duodenal and gastric ulcers. [2] Misoprostol and other prostaglandin analogues protect the lining of the gastrointestinal tract from harmful stomach acid and are especially indicated for the elderly on continuous doses of NSAIDs.
Ad
related to: indomethacin side effects in elderly