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Perioral dermatitis: This is a rash that occurs around the mouth and the eye region that has been associated with topical steroids. Ocular effects: Topical steroid drops are frequently used after eye surgery but can also raise intraocular pressure (IOP) and increase the risk of glaucoma , cataract , retinopathy as well as systemic adverse effects.
Along with the rash, atopic dermatitis can cause itchiness and dryness. It can also cause skin to feel warm and swollen. After the rash heals, the skin may have a discoloration to it, the AAD says.
Desonide is a low-potency topical corticosteroid anti-inflammatory that has been available since the 1970s. It is primarily used to treat atopic dermatitis (), seborrheic dermatitis, contact dermatitis and psoriasis in both adults and children.
Intermittent use of topical steroids for atopic dermatitis is safe and does not cause skin thinning. [6] [7] [8] Skin atrophy can occur with both prescription and over the counter steroids creams. [9] Low doses of prednisone by mouth can also result in skin atrophy.
Prednisone is a glucocorticoid medication mostly used to suppress the immune system and decrease inflammation in conditions such as asthma, COPD, and rheumatologic diseases. [3] It is also used to treat high blood calcium due to cancer and adrenal insufficiency along with other steroids . [ 3 ]
Topical steroid withdrawal, also known as red burning skin and steroid dermatitis, has been reported in people who apply topical steroids for 2 weeks or longer and then discontinue use. [ 4 ] [ 5 ] [ 2 ] [ 1 ] Symptoms affect the skin and include redness, a burning sensation, and itchiness, [ 2 ] which may then be followed by peeling.
It is a more potent derivative of triamcinolone, and is about eight times as potent as prednisone. [14] Most forms of triamcinolone acetonide are prescription drugs. In 2014, the U.S. Food and Drug Administration (FDA) made triamcinolone acetonide an over-the-counter drug in the United States in nasal spray form under the brand name Nasacort. [14]
Adverse reactions from the use of prednisolone include: [40] [7] Increased appetite, weight gain, nausea, and malaise; Increased risk of infection; Cardiovascular events; Dermatological effects including reddening of the face, bruising/skin discoloration, impaired wound healing, skin atrophy, skin rash, edema, and abnormal hair growth
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