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Antiviral drugs are different from antibiotics. Flu antiviral drugs are different from antiviral drugs used to treat other infectious diseases such as COVID-19. Antiviral drugs prescribed to treat COVID-19 are not approved or authorized to treat flu. [1]
Severe cases are most common in older adults (those older than 60 years, [73] and especially those older than 80 years). [100] Many developed countries do not have enough hospital beds per capita, which limits a health system's capacity to handle a sudden spike in the number of COVID-19 cases severe enough to require hospitalisation. [101]
Drugs are given only after confirmation of the lab tests. The drugs used in the treatment of mild COVID-19 cases are Paracetamol, Oseltamavir 150 mg and antibiotics if needed. Their vitals are monitored twice a day. [143] For moderate to severe COVID-19 cases in CCUs, the following drugs are used: [143] Azithromycin 500 mg, once daily for five ...
The most commonly used method for treating resistant viruses is combination therapy, which uses multiple antivirals in one treatment regimen. This is thought to decrease the likelihood that one mutation could cause antiviral resistance, as the antivirals in the cocktail target different stages of the viral life cycle. [ 54 ]
A common trial design for Phase II studies of possible COVID-19 drugs is randomized, placebo-controlled, blinded, and conducted at multiple sites, while determining more precise, effective doses and monitoring for adverse effects. [27]
A vial of Covaxin used at a private hospital in Bengaluru, India. On 6 December 2020, Bharat Biotech applied to the Drugs Controller General of India (DCGI), seeking emergency use authorisation. [60] It was the third firm after Serum Institute of India and Pfizer to apply under such provision. [61]
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[9] [10] These drugs had been further developed prior to the COVID-19 pandemic for other diseases including SARS. [11] The utility of targeting the 3CL protease in a real world setting was first demonstrated in 2018 when GC376 (a prodrug of GC373) was used to treat the previously 100% lethal cat coronavirus disease, feline infectious ...