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Brugia malayi is a filarial (arthropod-borne) nematode (roundworm), one of the three causative agents of lymphatic filariasis in humans. Lymphatic filariasis, also known as elephantiasis , is a condition characterized by swelling of the lower limbs.
Brugia is a genus for a group of small roundworms. They are among roundworms that cause the parasitic disease filariasis . [ 1 ] Specifically, of the three species known, Brugia malayi and Brugia timori cause lymphatic filariasis in humans; and Brugia pahangi and Brugia patei infect domestic cats, dogs and other animals.
Filariasis is a filarial infection caused by parasitic nematodes (roundworms) spread by different vectors.They are included in the list of neglected tropical diseases.. The most common type is lymphatic filariasis caused by three species of Filaria that are spread by mosquitoes.
Lymphatic filariasis is a human disease caused by parasitic worms known as filarial worms. [2] [3] Usually acquired in childhood, it is a leading cause of permanent disability worldwide, impacting over a hundred million people and manifesting itself in a variety of severe clinical pathologies [6] [7] While most cases have no symptoms, some people develop a syndrome called elephantiasis, which ...
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The life cycle of Brugia timori is very similar to that of Wuchereria bancrofti and Brugia malayi, leading to nocturnal periodicity of the disease symptoms. Eosinophilia is common during acute stages of infection. [citation needed] So far Brugia timori has only been found in the Lesser Sunda Islands of Indonesia.
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The heterogonic life cycle is advantageous to the parasite because it allows reproduction in the absence of a host. In the free-living cycle, the rhabditiform larvae passed in the stool can either molt twice and become infective filariform larvae (direct development) or molt four times and become free-living adult males and females that mate ...