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Magnet-assisted transfection is a transfection method which uses magnetic interactions to deliver DNA into target cells. Nucleic acids are associated with magnetic nanoparticles, and magnetic fields drive the nucleic acid-particle complexes into target cells, where the nucleic acids are released. [1] [2]
In 2010, Arnd Pralle and colleges showed that the first in vivo magneto-thermal stimulation of heat sensitive ion channel TRPV1 that employs magnetic nanoparticles as a transducer in C. elegans. [4] In 2012, Seung Chan Kim showed gene expression profile change of total human genome approximately 30,000 genes using 0.2T static magnetic fields. [5]
Magnetic reluctance, or magnetic resistance, is a concept used in the analysis of magnetic circuits. It is defined as the ratio of magnetomotive force (mmf) to magnetic flux . It represents the opposition to magnetic flux, and depends on the geometry and composition of an object.
It is the property of certain substances or phenomena that give rise to magnetic fields: =, where Φ is the magnetic flux and is the reluctance of the circuit. It can be seen that the magnetomotive force plays a role in this equation analogous to the voltage V in Ohm's law , V = IR , since it is the cause of magnetic flux in a magnetic circuit ...
The column consists of steel wool which increases the magnetic field gradient to maximize separation efficiency when the column is placed between the permanent magnets. Magnetic-activated cell sorting is a commonly used method in areas like immunology, cancer research, neuroscience, and stem cell research.
When it comes to insects' DNA, humans have a bit less in common. For example, fruit flies share 61 percent of disease-causing genes with humans, which was important when NASA studied the bugs to ...
3D cell culture methods have been developed to enable research into the behavior of cells in an environment that represents their interactions in-vivo more accurately [5].. 3D cell culturing by magnetic levitation uses biocompatible polymer-based reagents [2] to deliver magnetic nanoparticles to individual cells, so that an applied magnetic driver can levitate cells off the bottom of the cell ...
Magnetic complex reluctance (SI Unit: H −1) is a measurement of a passive magnetic circuit (or element within that circuit) dependent on sinusoidal magnetomotive force (SI Unit: At·Wb −1) and sinusoidal magnetic flux (SI Unit: T·m 2), and this is determined by deriving the ratio of their complex effective amplitudes.[Ref. 1-3] = ˙ ˙ = ˙ ˙ =