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Magnetic reluctance, or magnetic resistance, is a concept used in the analysis of magnetic circuits. It is defined as the ratio of magnetomotive force (mmf) to magnetic flux . It represents the opposition to magnetic flux, and depends on the geometry and composition of an object.
In 2010, Arnd Pralle and colleges showed that the first in vivo magneto-thermal stimulation of heat sensitive ion channel TRPV1 that employs magnetic nanoparticles as a transducer in C. elegans. [4] In 2012, Seung Chan Kim showed gene expression profile change of total human genome approximately 30,000 genes using 0.2T static magnetic fields. [5]
Eukaryotes initiate DNA replication at multiple points in the chromosome, so replication forks meet and terminate at many points in the chromosome. Because eukaryotes have linear chromosomes, DNA replication is unable to reach the very end of the chromosomes. Due to this problem, DNA is lost in each replication cycle from the end of the chromosome.
Magnet-assisted transfection is a transfection method which uses magnetic interactions to deliver DNA into target cells. Nucleic acids are associated with magnetic nanoparticles, and magnetic fields drive the nucleic acid-particle complexes into target cells, where the nucleic acids are released. [1] [2]
During DNA replication, the replisome will unwind the parental duplex DNA into a two single-stranded DNA template replication fork in a 5' to 3' direction. The leading strand is the template strand that is being replicated in the same direction as the movement of the replication fork.
Magnetic complex reluctance (SI Unit: H −1) is a measurement of a passive magnetic circuit (or element within that circuit) dependent on sinusoidal magnetomotive force (SI Unit: At·Wb −1) and sinusoidal magnetic flux (SI Unit: T·m 2), and this is determined by deriving the ratio of their complex effective amplitudes.[Ref. 1-3] = ˙ ˙ = ˙ ˙ =
The replication fork consists of a group of proteins that influence the activity of DNA replication. In order for the replication fork to stall, the cell must possess a certain number of stalled forks and arrest length. The replication fork is specifically paused due to the stalling of helicase and polymerase activity, which are linked together ...
After that, E. coli cells with only 15 N in their DNA were transferred to a 14 N medium and were allowed to divide; the progress of cell division was monitored by microscopic cell counts and by colony assay. DNA was extracted periodically and was compared to pure 14 N DNA and 15 N DNA. After one replication, the DNA was found to have ...