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In short, melasma is a chronic skin condition that appears as darkened areas on the face due to an overproduction of melanin, says Gina Charles, MO, a family physician specializing in skincare. It ...
It is caused by melanocyte or melanin depletion, or a decrease in the amino acid tyrosine, which is used by melanocytes to make melanin. [2] Some common genetic causes include mutations in the tyrosinase gene or OCA2 gene. [3] [4] As melanin pigments tend to be in the skin, eye, and hair, these are the commonly affected areas in those with ...
In addition, many skin care ingredients can help in the form of eye creams. Caffeine is a potent vasoconstrictor that has been proven to improve the look of dark circles [16] by constricting, or tightening, the dilated vessels under eyes. Vitamin C can help brighten hyperpigmentation as well as thicken the dermal layer of skin which conceals ...
The affected eye may be hyperpigmented (hyperchromic) or hypopigmented (hypochromic). [3] In humans, an increase of melanin production in the eyes indicates hyperplasia of the iris tissues, whereas a lack of melanin indicates hypoplasia. The term is derived from Ancient Greek: ἕτερος, héteros "different" and χρῶμα, chrôma "color ...
Melanin is the protein that creates skin, eye and hair color. More melanin means darker eyes, hair or skin. The color of the melanin in the eyes is determined by three other genes, EYCL1, 2 and 3.
Many forms of hyperpigmentation are caused by an excess production of melanin. [4] Hyperpigmentation can be diffuse or focal, affecting such areas as the face and the back of the hands. Melanin is produced by melanocytes at the lower layer of the epidermis. Melanin is a class of pigment responsible for producing color in the body in places such ...
Postinflammatory hyperpigmentation develops after the original symptoms of an inflammatory skin condition disappear. Common triggers include acne lesions, cuts, burns, or skin conditions like eczema. [1] Additionally, UV sun exposure and sunburn are involved in the development, darkening, and expansion of hyperpigmented skin lesions. [2]
Melanin is produced through a multistage chemical process known as melanogenesis, where the oxidation of the amino acid tyrosine is followed by polymerization. Pheomelanin is a cysteinated form containing polybenzothiazine portions that are largely responsible for the red or yellow tint given to some skin or hair colors. Neuromelanin is found ...