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Doxycycline is a broad-spectrum antibiotic of the tetracycline class used in the treatment of infections caused by bacteria and certain parasites. [1] It is used to treat bacterial pneumonia, acne, chlamydia infections, Lyme disease, cholera, typhus, and syphilis. [1] It is also used to prevent malaria.
The Centers for Disease Control and Prevention finalized its endorsement of taking doxycycline after unprotected sex as a way to prevent chlamydia, gonorrhea or syphilis infections.
A new proven protocol in which doxycycline is used to prevent sexually transmitted infections — called doxyPEP — has been an apparent sleeper hit among gay and bisexual men.
Tetracyclines remain the treatment of choice for infections caused by chlamydia (trachoma, psittacosis, salpingitis, urethritis and L. venereum infection), Rickettsia (typhus, Rocky Mountain spotted fever), brucellosis and spirochetal infections (Lyme disease/borreliosis and syphilis). [2] They are also used in veterinary medicine. [2]
Treatment at this stage solely limits further progression of the disease and has a limited effect on damage which has already occurred. [3] Serologic cure can be measured when the non-treponemal titers decline by a factor of 4 or more in 6–12 months in early syphilis or 12–24 months in late syphilis. [21]
There is a cure. Syphilis is curable with a course of antibiotics. The CDC recommends an injection of long-acting penicillin G benzathine to treat the primary, secondary or early latent stages of ...
The drug was used to treat syphilis in the first half of the 20th century. In 1908, Ehrlich received the Nobel Prize in Physiology or Medicine for his contributions to immunology. [137] Hata was nominated for the Nobel Prize in Chemistry in 1911 and for the Nobel Prize in Physiology or Medicine in 1912 and 1913. [138]
By 1947, penicillin had been shown to be an effective cure for early syphilis and was becoming widely used to treat the disease. [98] Its use in later syphilis, however, was still unclear. [ 99 ] Study directors continued the study and did not offer the participants treatment with penicillin. [ 98 ]