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Mammillary bodies, and their projections to the anterior thalamus via the mammillothalamic tract, are important for recollective memory. [7] According to studies of rats with mammillary body lesions, damage to the medial mammillary nucleus lead to spatial memory deficits.
The mammillary bodies are an important part of the Papez circuit. If there is damage, such as loss of neurons and/or myelination, to the mammillary bodies, the Papez circuit can be severely affected. There will be a disruption in the connecting parts of the system.
The mammillary bodies are two clusters of cell bodies found at the ends of the posterior fibres of the fornix within the diencephalon. The mammillary bodies relay information from the hippocampal formation (via the fornix) to the thalamus (via the mammillothalamic tract). The mammillary bodies are integral parts of the limbic system and have ...
Paul Broca coined the term based on its physical location in the brain, sandwiched between two functionally different components. The limbic system is a term that was introduced in 1949 by the American physician and neuroscientist, Paul D. MacLean .
Mammillary nuclei (part of mammillary bodies) Posterior nucleus; Lateral area Posterior part of Lateral nucleus; Surface Median eminence; Mammillary bodies; Pituitary stalk (infundibulum) Optic chiasm; Subfornical organ; Periventricular nucleus; Tuber cinereum. Tuberal nucleus; Tuberomammillary nucleus; Tuberal region; Mammillary nucleus
The posterior fibers (called the postcommissural fornix) of each side continue through the hypothalamus to the mammillary bodies; then to the anterior nuclei of thalamus via the mammillothalamic tract. The anterior fibers (precommissural fornix) end at the septal nuclei of the basal forebrain and nucleus accumbens of each half of the brain.
The mammillary bodies directly or indirectly connect to the amygdala, hippocampus, and thalami as major structures in the limbic system. [6] The mammillothalamic tract carries signals from the mammillary bodies via the anterior thalamus to support spatial memory .
The tuber cinereum is a convex mass of grey matter, [3]: 495 a ventral/inferior distention of the hypothalamus forming the floor of the third ventricle. [citation needed] The portion of the tuber cinerum at the base of the infundibulum (pituitary stalk) is the median eminence; [2] the infundibulum extends ventrally/inferiorly from the median eminence to become continuous with the infundibulum.