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  2. Valaciclovir - Wikipedia

    en.wikipedia.org/wiki/Valaciclovir

    It is a prodrug, which works after being converted to aciclovir in a person's body. [2] Valaciclovir was patented in 1987 and came into medical use in 1995. [3] [4] It is on the World Health Organization's List of Essential Medicines. [5] It is available as a generic medication. [6]

  3. Jarisch–Herxheimer reaction - Wikipedia

    en.wikipedia.org/wiki/Jarisch–Herxheimer_reaction

    It usually manifests in 1–3 hours after the first dose of antibiotics as fever, chills, rigor, hypotension, headache, tachycardia, hyperventilation, vasodilation with flushing, myalgia (muscle pain), exacerbation of skin lesions and anxiety. The intensity of the reaction indicates the severity of inflammation.

  4. Post-exposure prophylaxis - Wikipedia

    en.wikipedia.org/wiki/Post-exposure_prophylaxis

    To be most effective, treatment should begin within an hour of exposure. [23] After 72 hours PEP is much less effective, and may not be effective at all. [22] Prophylactic treatment for HIV typically lasts four weeks. [22] [24] While there is compelling data to suggest that PEP after HIV exposure is effective, there have been cases where it has ...

  5. Cold sore - Wikipedia

    en.wikipedia.org/wiki/Cold_sore

    Treatment with oral antivirals such as acyclovir in children within 72 hours of illness onset has shown to shorten duration of fever, odynophagia, and lesions, and to reduce viral shedding. [35] [1] For patient with mild to moderate symptoms, local anaesthetic such as lidocaine for pain without antiviral may be sufficient. However, those with ...

  6. Biological half-life - Wikipedia

    en.wikipedia.org/wiki/Biological_half-life

    In clinical practice, this means that it takes 4 to 5 times the half-life for a drug's serum concentration to reach steady state after regular dosing is started, stopped, or the dose changed. So, for example, digoxin has a half-life (or t ⁠ 1 / 2 ⁠ ) of 24–36 h; this means that a change in the dose will take the best part of a week to ...

  7. Brivudine - Wikipedia

    en.wikipedia.org/wiki/Brivudine

    Highest blood plasma concentrations are reached after one hour. Brivudine is almost completely (>95%) bound to plasma proteins . Terminal half-life is 16 hours; 65% of the substance are found in the urine and 20% in the faeces, mainly in form of an acetic acid derivative (which is not detectable in the plasma), but also other water-soluble ...

  8. Does Medicare cover Ozempic? Yes — but it depends on your Rx

    www.aol.com/finance/does-medicare-cover-ozempic...

    The average cost Medicare Part D paid per dose was $468.24, increased from $452.72 in 2021. Does Medicare cover diabetes testing supplies? Yes, Medicare Part B generally covers blood glucose ...

  9. Involuntary commitment - Wikipedia

    en.wikipedia.org/wiki/Involuntary_commitment

    Commitment proceedings often follow a period of emergency hospitalization, during which an individual with acute psychiatric symptoms is confined for a relatively short duration (e.g. 72 hours) in a treatment facility for evaluation and stabilization by mental health professionals who may then determine whether further civil commitment is ...