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Potential Mechanisms of Cancer-Related Hypercoagulability: Cancer-associated thrombosis can result from: (1) stasis, i.e., direct pressure on blood vessels by the tumor mass, poor performance status, and bed rest following surgical procedures; (2) iatrogenic, due to treatment with antineoplastic medications; and (3) secretion of heparanase from ...
Peripheral veinous disease, on the other hand, refers to problems with veins—the vessels that bring the blood back to the heart. [18] The classic symptom is leg pain when walking, which resolves with rest and is known as intermittent claudication. [2]
Buerger's disease – inflammation and swelling in small blood vessels, causing the vessels to narrow or become blocked by blood clots. [18] Raynaud syndrome – a peripheral vascular disorder that causes constriction of the peripheral blood vessels in the fingers and toes when a person is cold or experiencing stress. [19]
The average mean age of affected patients is 60 years. [16] Thrombophlebitis can develop along the arm, back, or neck veins, the leg is by far the most common site. When it occurs in the leg, the great saphenous vein is usually involved, although other locations are possible. [18]
An embolism involves the occlusion of blood vessels by an embolus. [1] Arterial occlusion by an embolus is termed 'arterial embolism'. An embolus is an agent that blocks blood flow by physically obstructing blood vessels. [1] This includes gas bubbles, [18] fatty deposits, amniotic fluid, [19] blood clots, and foreign material. Arterial emboli ...
Lymphangiosarcoma is a rare cancer which occurs in long-standing cases of primary or secondary lymphedema (swelling due to lymphatic system obstruction). It involves either the upper or lower lymphedematous extremities but is most common in upper extremities. [1]
Leg ulcer; CVI in the leg may cause the following: Venous stasis; Venous ulcers [8] Stasis dermatitis, [8] also known as varicose eczema; Contact dermatitis, [8] a disrupted epidermal barrier due to venous insufficiency, making patients more susceptible than the general population to contact sensitization and subsequent dermatitis.
Angiosarcoma is a rare and aggressive cancer that starts in the endothelial cells that line the walls of blood vessels or lymphatic vessels.Since they are made from vascular lining, they can appear anywhere and at any age, but older people are more commonly affected, and the skin is the most affected area, with approximately 60% of cases being cutaneous (skin).