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  2. The U.S. Food and Drug Administration expanded approval for Johnson & Johnson’s nasal spray, Spravato, to allow it to be used as a standalone treatment for patients with severe depression, the ...

  3. FDA-approved nasal spray for severe depression can lead to ...

    www.aol.com/fda-approved-nasal-spray-severe...

    The Food and Drug Administration (FDA) recently approved the nasal spray Spravato for the treatment of major depression in people who have not responded to at least two oral antidepressants.

  4. Does Medicare cover ketamine infusions for mental health ...

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    Spravato is the brand name for an esketamine nasal spray that the FDA has approved for treatment-resistant depression. A doctor may prescribe the drug for depression that has not responded to ...

  5. Ketamine-assisted psychotherapy - Wikipedia

    en.wikipedia.org/wiki/Ketamine-assisted...

    Since 2010, ketamine has been prescribed off-label to patients with severe depression with the informed consent of patients. [26] In 2019, the FDA approved the use of esketamine (Spravato) as a nasal spray, in conjunction with an oral antidepressant, for treatment-resistant depression in adults.

  6. Esketamine - Wikipedia

    en.wikipedia.org/wiki/Esketamine

    Esketamine, sold under the brand names Spravato (for depression) and Ketanest (for anesthesia) among others, [10] [12] is the S(+) enantiomer of ketamine. [5] [13] It is a dissociative hallucinogen drug used as a general anesthetic and as an antidepressant for treatment of depression.

  7. Ketamine - Wikipedia

    en.wikipedia.org/wiki/Ketamine

    Ketamine may partially improve depressive symptoms [19] among people with bipolar depression at 24 hours after treatment, but not three or more days. [66] Potentially, ten more people with bipolar depression per 1000 may experience brief improvement, but not the cessation of symptoms, one day following treatment.

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