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Lymphocytic choriomeningitis (LCM) is a rodent-borne viral infectious disease that presents as aseptic meningitis, encephalitis or meningoencephalitis.Its causative agent is lymphocytic choriomeningitis mammarenavirus (LCMV), a member of the family Arenaviridae.
The number of cases of encephalitis has not changed much over time, with about 250,000 cases a year from 2005 to 2015 in the US. Approximately seven per 100,000 people were hospitalized for encephalitis in the US during this time. [34] In 2015, encephalitis was estimated to have affected 4.3 million people and resulted in 150,000 deaths worldwide.
The neurological manifestations can be either acute or subacute and usually develop within six weeks. The clinical manifestations include behavioral and psychiatric symptoms, autonomic disturbances, movement disorders, and seizures. [1] Autoimmune encephalitis can result from a number of autoimmune diseases including: Rasmussen encephalitis
Acute necrotizing encephalopathy (ANE) or sometimes necrotizing encephalitis or infection-induced acute encephalopathy (IIAE) is a rare type of brain disease (encephalopathy) that occurs following a viral infection. [4] Most commonly, it develops secondary to infection with influenza A, influenza B, and the human herpes virus 6. ANE can be ...
Certain patterns of activity can be indicative of brain disease. In the case of anti-Hu encephalitis, temporal lobe electrical activity changes and the length of certain electrical waves known as delta and theta waves become slowed. [1] Before the diagnosis can be made, other causes of disease need to be ruled out.
The estimated number of cases of the disease is 1.5 per million people per year. [7] According to the California Encephalitis Project, the disease has a higher incidence than its individual viral counterparts in patients younger than 30. [35] The largest case series as of 2013 characterized 577 people with anti-NMDA receptor encephalitis.
Aseptic meningitis is a disease that can depend on the patient's age, however, research has shown some distinct symptoms that indicate the possibility of aseptic meningitis. A variety of patients notice a change in body temperatures (higher than normal temperatures 38-40 °C), marked with the possibility of vomiting, headaches, firm neck pain ...
For some forms of viral encephalitis, such as Eastern equine encephalitis and Japanese encephalitis, there may be a significant amount of necrosis of nerve cells. Following encephalitis caused by arboviruses, calcification may occur in the CNS, especially among children. Herpes simplex encephalitis tends to produce necrotic lesions in the CNS. [1]
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